TY - JOUR
T1 - Association between daily ambulatory activity patterns and exercise performance in patients with intermittent claudication
AU - Gardner, Andrew W.
AU - Montgomery, Polly S.
AU - Scott, Kristy J.
AU - Blevins, Steve M.
AU - Afaq, Azhar
AU - Nael, Raha
N1 - Funding Information:
This research was supported by grants from the National Institute on Aging (NIA) (R01-AG-16685, and R01-AG-24296; AWG), by a Oklahoma Center for the Advancement of Science and Technology grant (HR04-113S; AWG), and by the University of Oklahoma Health Sciences Center General Clinical Research Center grant (M01-RR-14467), sponsored by the National Center for Research Resources from the National Institutes of Health.
PY - 2008/11
Y1 - 2008/11
N2 - Purpose: To determine the association between daily ambulatory activity patterns and exercise performance in patients with intermittent claudication. Methods: One hundred thirty-three patients limited by intermittent claudication participated in this study. Patients were assessed on their ambulatory activity patterns for 1 week with a small, lightweight step activity monitor attached to the ankle using elastic velcro straps above the lateral malleolus of the right leg. The step activity monitor recorded the number of strides taken on a minute-to-minute basis and the time spent ambulating. Patients also were characterized on ankle-brachial index (ABI), ischemic window (IW) after a treadmill test, as well as initial claudication distance (ICD), and absolute claudication distance (ACD) during treadmill exercise. Results: The patient characteristics (mean ± SD) were as follows: ABI = 0.71 ± 0.23, IW = 0.54 ± 0.72 mm Hg · min · meter-1, ICD = 236 ± 198 meters, and ACD = 424 ± 285 meters. The patients took 3366 ± 1694 strides/day, and were active for 272 ± 103 min/day. The cadence for the 30 highest, consecutive minutes of each day (15.1 ± 7.2 strides/min) was correlated with ICD (r = 0.316, P < .001) and ACD (r = 0.471, P < 0.001), and the cadence for the 60 highest, consecutive minutes of each day (11.1 ± 5.4 strides/min) was correlated with ICD (r = 0.290, P < .01) and ACD (r = 0.453, P < .001). Similarly, the cadences for the highest 1, 5, and 20 consecutive minutes, and the cadence for the 30 highest, nonconsecutive minutes all were correlated with ICD and ACD (P < .05). None of the ambulatory cadences were correlated with ABI (P > .05) or with ischemic window (P > .05). Conclusion: Daily ambulatory cadences are associated with severity of intermittent claudication, as measured by ACD and ICD, but not with peripheral hemodynamic measures.
AB - Purpose: To determine the association between daily ambulatory activity patterns and exercise performance in patients with intermittent claudication. Methods: One hundred thirty-three patients limited by intermittent claudication participated in this study. Patients were assessed on their ambulatory activity patterns for 1 week with a small, lightweight step activity monitor attached to the ankle using elastic velcro straps above the lateral malleolus of the right leg. The step activity monitor recorded the number of strides taken on a minute-to-minute basis and the time spent ambulating. Patients also were characterized on ankle-brachial index (ABI), ischemic window (IW) after a treadmill test, as well as initial claudication distance (ICD), and absolute claudication distance (ACD) during treadmill exercise. Results: The patient characteristics (mean ± SD) were as follows: ABI = 0.71 ± 0.23, IW = 0.54 ± 0.72 mm Hg · min · meter-1, ICD = 236 ± 198 meters, and ACD = 424 ± 285 meters. The patients took 3366 ± 1694 strides/day, and were active for 272 ± 103 min/day. The cadence for the 30 highest, consecutive minutes of each day (15.1 ± 7.2 strides/min) was correlated with ICD (r = 0.316, P < .001) and ACD (r = 0.471, P < 0.001), and the cadence for the 60 highest, consecutive minutes of each day (11.1 ± 5.4 strides/min) was correlated with ICD (r = 0.290, P < .01) and ACD (r = 0.453, P < .001). Similarly, the cadences for the highest 1, 5, and 20 consecutive minutes, and the cadence for the 30 highest, nonconsecutive minutes all were correlated with ICD and ACD (P < .05). None of the ambulatory cadences were correlated with ABI (P > .05) or with ischemic window (P > .05). Conclusion: Daily ambulatory cadences are associated with severity of intermittent claudication, as measured by ACD and ICD, but not with peripheral hemodynamic measures.
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U2 - 10.1016/j.jvs.2008.06.062
DO - 10.1016/j.jvs.2008.06.062
M3 - Article
C2 - 18771878
AN - SCOPUS:55049112948
SN - 0741-5214
VL - 48
SP - 1238
EP - 1244
JO - Journal of Vascular Surgery
JF - Journal of Vascular Surgery
IS - 5
ER -