TY - JOUR
T1 - Association between indicators of disability burden and subsequent depression among older persons
AU - Barry, Lisa C.
AU - Soulos, Pamela R.
AU - Murphy, Terrence E.
AU - Kasl, Stanislav V.
AU - Gill, Thomas M.
N1 - Funding Information:
Funding This work was supported by the National Institute on Aging at the National Institutes of Health (grant numbers R37AG17560, R01AG022993, and K24AG021507 to TG and K01AG031324 to LB). The study was conducted at the Yale Claude D. Pepper Older Americans Independence Center (grant number P30AG21342).
PY - 2013/3/1
Y1 - 2013/3/1
N2 - BackgroundDisability is associated with depression in older persons, yet the effect of disability burden on the likelihood of being depressed is uncertain.Methods.A total of 754 community-living persons, aged ≥70, underwent monthly assessments in four essential activities of daily living and assessments of depression (yes/no) every 18 months for up to 108 months. Within each 18-month person-interval, participants' disability burden was operationalized as none or any, and according to severity (none, mild, or severe) and chronicity (none, nonchronic, or chronic) given the highest level of severity or chronicity experienced during a given 18-month interval, respectively. A variable combining severity and chronicity (none, nonchronic mild, nonchronic severe, chronic-mild, or chronic-severe) was also created. Using generalized estimating equations, we evaluated the association between each indicator of disability burden and subsequent depression. ResultsParticipants who had any versus no disability during the previous 18 months were 65% more likely to experience subsequent depression (OR = 1.65; 95% confidence interval [CI] 1.34, 2.02). Quantifying severity (mild disability vs. none, OR = 1.43; 95% CI: 1.15, 1.79; severe disability vs. none, OR = 2.07; 95% CI 1.56, 2.74) and chronicity (nonchronic disability vs. none, OR = 1.44; 95% CI 1.13, 1.83; chronic disability vs. none, OR = 1.96; 95% CI 1.50, 2.55) indicated increasingly stronger associations with subsequent depression, with the highest likelihood of subsequent depression (OR = 2.42; 95% CI 1.78, 3.30) observed among participants with chronic-severe disability. ConclusionsQuantifying the magnitude of disability burden, particularly on the basis of severity and chronicity, provides additional information regarding the likelihood of experiencing subsequent depression among older persons.
AB - BackgroundDisability is associated with depression in older persons, yet the effect of disability burden on the likelihood of being depressed is uncertain.Methods.A total of 754 community-living persons, aged ≥70, underwent monthly assessments in four essential activities of daily living and assessments of depression (yes/no) every 18 months for up to 108 months. Within each 18-month person-interval, participants' disability burden was operationalized as none or any, and according to severity (none, mild, or severe) and chronicity (none, nonchronic, or chronic) given the highest level of severity or chronicity experienced during a given 18-month interval, respectively. A variable combining severity and chronicity (none, nonchronic mild, nonchronic severe, chronic-mild, or chronic-severe) was also created. Using generalized estimating equations, we evaluated the association between each indicator of disability burden and subsequent depression. ResultsParticipants who had any versus no disability during the previous 18 months were 65% more likely to experience subsequent depression (OR = 1.65; 95% confidence interval [CI] 1.34, 2.02). Quantifying severity (mild disability vs. none, OR = 1.43; 95% CI: 1.15, 1.79; severe disability vs. none, OR = 2.07; 95% CI 1.56, 2.74) and chronicity (nonchronic disability vs. none, OR = 1.44; 95% CI 1.13, 1.83; chronic disability vs. none, OR = 1.96; 95% CI 1.50, 2.55) indicated increasingly stronger associations with subsequent depression, with the highest likelihood of subsequent depression (OR = 2.42; 95% CI 1.78, 3.30) observed among participants with chronic-severe disability. ConclusionsQuantifying the magnitude of disability burden, particularly on the basis of severity and chronicity, provides additional information regarding the likelihood of experiencing subsequent depression among older persons.
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U2 - 10.1093/gerona/gls179
DO - 10.1093/gerona/gls179
M3 - Article
C2 - 22967459
AN - SCOPUS:84873626261
SN - 1079-5006
VL - 68
SP - 286
EP - 292
JO - Journals of Gerontology - Series A Biological Sciences and Medical Sciences
JF - Journals of Gerontology - Series A Biological Sciences and Medical Sciences
IS - 3
ER -