Association of Vaccination in Pregnancy With Newborn Hepatitis B Vaccine Receipt

INTRODUCTION: The authors evaluated factors associated with neonatal hepatitis B vaccination (HepB), including prenatal vaccinations, race, ethnicity, neonatal disposition, parity, and maternal age to identify potential areas of engagement to improve maternal and child health. METHODS: The authors conducted a retrospective cohort study of patients who received prenatal care and delivered at an academic tertiary care hospital in central Pennsylvania from 2015-2020. A multiple logistic regression model was used to assess factors associated with newborn receipt of HepB. RESULTS: Prenatal vaccination was significantly (P < .0001) associated with subsequent neonatal HepB vaccination in the hospital following birth. Race, Hispanic ethnicity, age at delivery, neonatal disposition, and parity were not shown to be associated with HepB vaccine uptake. CONCLUSION: Prenatal vaccination was significantly associated with neonatal in-hospital HepB vaccine uptake.