Atlas of the Radical SAM Superfamily: Divergent Evolution of Function Using a “Plug and Play” Domain

Keyphrases

• Evolution of Functions 100%
• Radical SAM 100%
• Plug-and-play 100%
• Divergent Evolution 100%
• Reaction Types 66%
• Similarity-based 66%
• Metabolism 33%
• Structure Function 33%
• Biogenesis 33%
• Binding Motif 33%
• Structural Features 33%
• Domain-specific Architecture 33%
• Similarity Network 33%
• Unknown Function 33%
• Functional Information 33%
• Biological Significance 33%
• Phylogenetic Distribution 33%
• Radical Intermediates 33%
• Reaction Range 33%
• 5′-Deoxyadenosyl Radical 33%
• Structure-function Relationship 33%
• Subgrouping 33%
• Complex Domain 33%
• New Reactions 33%
• Function Prediction 33%

Biochemistry, Genetics and Molecular Biology

• Nucleic Acid Modification 33%