Atrial Fibrillation in Heart Failure: Prognostic Significance and Management

Gerald Naccarelli, B. John Hynes, Deborah Wolbrette, Luna Bhatta, Mazhar Khan, Soraya Samii, Jerry C. Luck

Research output: Contribution to journalArticlepeer-review

32 Scopus citations


Atrial fibrillation and congestive heart failure are commonly occurring cardiac disorders that often exist concomitantly. The prognostic significance of the presence or absence of atrial fibrillation, as an independent risk factor, in patients with heart failure remains controversial. Antiarrhythmic drugs with good hemodynamic profiles and neutral effects on survival are preferred treatments for converting atrial fibrillation and maintaining sinus rhythm. Other standard therapies for congestive heart failure, such as angiotensin-converting enzyme inhibitors, angiotensin receptor blockers, and beta-blockers also have a role in the treatment of these coexisting disease states. The article presents an overview of atrial fibrillation in patients with heart failure and reviews the prevalence, prognostic significance, and efficacy of various antiarrhythmic agents for the conversion and maintenance of sinus rhythm.

Original languageEnglish (US)
Pages (from-to)S281-S286
JournalJournal of cardiovascular electrophysiology
Issue number12 SUPPL.
StatePublished - Dec 2003

All Science Journal Classification (ASJC) codes

  • Cardiology and Cardiovascular Medicine
  • Physiology (medical)


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