Atrial Septal Defect

Elisa A. Bradley, Ali N. Zaidi

Research output: Contribution to journalReview articlepeer-review

29 Scopus citations


Atrial septal defects are common congenital heart defects, characterized by insufficient/absent tissue at the interatrial septum. An unrepaired defect may be associated with right heart volume overload, atrial arrhythmia or pulmonary arterial hypertension. The 3 major types of atrial septal defect are: ostium secundum defect, ostium primum defect, and sinus venosus. Characteristic physical findings include a midsystolic pulmonary flow or ejection murmur, accompanied by a fixed split-second heart sound. Small defects may spontaneously close; larger defects may persist and result in hemodynamic and clinical sequelae requiring percutaneous or surgical intervention. Severe pulmonary arterial hypertension is a contraindication to closure.

Original languageEnglish (US)
Pages (from-to)317-324
Number of pages8
JournalCardiology Clinics
Issue number3
StatePublished - Aug 2020

All Science Journal Classification (ASJC) codes

  • Cardiology and Cardiovascular Medicine


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