TY - JOUR
T1 - Atypical case of syphilitic hepatitis
AU - Goldberg, Elliott
AU - Edwards, Bathai
AU - Krill, Kaleigh
N1 - Publisher Copyright:
© BMJ Publishing Group Limited 2021. No commercial re-use. See rights and permissions. Published by BMJ.
PY - 2021/3/17
Y1 - 2021/3/17
N2 - A 31-year-old immunocompetent, heterosexual man with no relevant medical history presented with 1 week of jaundice, abdominal pain, cough and headache. Examination revealed scleral icterus, right upper quadrant tenderness and hepatomegaly. Initial investigations revealed hyperbilirubinaemia and elevated transaminases. Serum studies were positive for antinuclear antibodies, antimitochondrial antibodies, and herpes simplex virus IgM. Despite being started on intravenous acyclovir, his bilirubin and transaminase levels continued to rise. He was subsequently tested for syphilis given his maculopapular rash on the soles of his feet and it returned positive. He improved clinically with the initiation of penicillin. In this case, we will discuss the presentation, diagnosis and treatment of syphilitic hepatitis.
AB - A 31-year-old immunocompetent, heterosexual man with no relevant medical history presented with 1 week of jaundice, abdominal pain, cough and headache. Examination revealed scleral icterus, right upper quadrant tenderness and hepatomegaly. Initial investigations revealed hyperbilirubinaemia and elevated transaminases. Serum studies were positive for antinuclear antibodies, antimitochondrial antibodies, and herpes simplex virus IgM. Despite being started on intravenous acyclovir, his bilirubin and transaminase levels continued to rise. He was subsequently tested for syphilis given his maculopapular rash on the soles of his feet and it returned positive. He improved clinically with the initiation of penicillin. In this case, we will discuss the presentation, diagnosis and treatment of syphilitic hepatitis.
UR - https://www.scopus.com/pages/publications/85103007987
UR - https://www.scopus.com/pages/publications/85103007987#tab=citedBy
U2 - 10.1136/bcr-2020-237851
DO - 10.1136/bcr-2020-237851
M3 - Article
C2 - 33731401
AN - SCOPUS:85103007987
SN - 1757-790X
VL - 14
JO - BMJ case reports
JF - BMJ case reports
IS - 3
M1 - e237851
ER -
