Abstract
AIn this Letter, the isotopologue used to demonstrate hydrogen atom abstraction from CTP was incorrectly identified as 2′,3′,4′,5′,5-deutero-CTP, whereas the isotopologue we used was 3′,4′,5′,5-deutero-CTP. (Boldface indicates where changes were made.) In the main text, the sentence “Incubation of rVIP with SAM and CTP deuterated at the 2′, 3′, 4′, 5′ and 5 positions (deuCTP), increased the −m/z of 5ʹ-dA from 250.1 to 251.1, consistent with the transfer of one deuterium from deuCTP to 5ʹ-dA.” should have read “Incubation of rVIP with SAM and CTP deuterated at the 3′, 4′, 5′ and 5 positions (deuCTP) increased the −m/z of 5ʹ-dA from 250.1 to 251.1, consistent with the transfer of one deuterium from deuCTP to 5ʹ-dA.”. In the Extended Data Fig. 3 legend the sentence “When rVIP was incubated with SAM and CTP deuterated at the 2′, 3′, 4′, 5′ and 5 positions (deuCTP), the −m/z of 5′-dA increased from 250.1 to 251.1, consistent with the transfer of one deuterium from deuCTP to 5′-dA•.” should have read: “When rVIP was incubated with SAM and CTP deuterated at the 3′, 4′, 5′ and 5 positions (deuCTP), the −m/z of 5′-dA increased from 250.1 to 251.1, consistent with the transfer of one deuterium from deuCTP to 5′-dA•.”
| Original language | English (US) |
|---|---|
| Pages (from-to) | E15 |
| Journal | Nature |
| Volume | 583 |
| Issue number | 7814 |
| DOIs |
|
| State | Published - Jul 2 2020 |
All Science Journal Classification (ASJC) codes
- General
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