Author Correction: A naturally occurring antiviral ribonucleotide encoded by the human genome (Nature, (2018), 558, 7711, (610-614), 10.1038/s41586-018-0238-4)

  • Anthony S. Gizzi
  • , Tyler L. Grove
  • , Jamie J. Arnold
  • , Joyce Jose
  • , Rohit K. Jangra
  • , Scott J. Garforth
  • , Quan Du
  • , Sean M. Cahill
  • , Natalya G. Dulyaninova
  • , James D. Love
  • , Kartik Chandran
  • , Anne R. Bresnick
  • , Craig E. Cameron
  • , Steven C. Almo

Research output: Contribution to journalComment/debatepeer-review

Abstract

AIn this Letter, the isotopologue used to demonstrate hydrogen atom abstraction from CTP was incorrectly identified as 2′,3′,4′,5′,5-deutero-CTP, whereas the isotopologue we used was 3′,4′,5′,5-deutero-CTP. (Boldface indicates where changes were made.) In the main text, the sentence “Incubation of rVIP with SAM and CTP deuterated at the 2′, 3′, 4′, 5′ and 5 positions (deuCTP), increased the −m/z of 5ʹ-dA from 250.1 to 251.1, consistent with the transfer of one deuterium from deuCTP to 5ʹ-dA.” should have read “Incubation of rVIP with SAM and CTP deuterated at the 3′, 4′, 5′ and 5 positions (deuCTP) increased the −m/z of 5ʹ-dA from 250.1 to 251.1, consistent with the transfer of one deuterium from deuCTP to 5ʹ-dA.”. In the Extended Data Fig. 3 legend the sentence “When rVIP was incubated with SAM and CTP deuterated at the 2′, 3′, 4′, 5′ and 5 positions (deuCTP), the −m/z of 5′-dA increased from 250.1 to 251.1, consistent with the transfer of one deuterium from deuCTP to 5′-dA•.” should have read: “When rVIP was incubated with SAM and CTP deuterated at the 3′, 4′, 5′ and 5 positions (deuCTP), the −m/z of 5′-dA increased from 250.1 to 251.1, consistent with the transfer of one deuterium from deuCTP to 5′-dA•.”

Original languageEnglish (US)
Pages (from-to)E15
JournalNature
Volume583
Issue number7814
DOIs
StatePublished - Jul 2 2020

All Science Journal Classification (ASJC) codes

  • General

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