Automated Apparatus for the Extraction and Enrichment of 2,3,7,8-Tetrachlorodibenzo-p-dioxin in Human Adipose Tissue

Chester R. Lapeza; Donald G. Patterson; John A. Liddle

doi:10.1021/ac00295a011

Automated Apparatus for the Extraction and Enrichment of 2,3,7,8-Tetrachlorodibenzo-p-dioxin in Human Adipose Tissue

Chester R. Lapeza, Donald G. Patterson, John A. Liddle

Forensic Science Program

Research output: Contribution to journal › Article › peer-review

43 Scopus citations

Abstract

An apparatus is described for the automation of the first part of a proven method for part-per-trillion dioxin analysis. A microprocessor controls the valves and solvent flow for the sequential extraction and enrichment of five tissue samples over a 20-h period. Sample and solvent selection for the multicolumn system and reversed flow elution, fraction collection, and column regeneration are all accomplished without operator attention. The time required by the analyst per sample has been reduced 50% compared with the totally manual method, resulting in greater throughput and lower personnel costs. The apparatus can be easily assembled with commercially available components.

Original language	English (US)
Pages (from-to)	713-716
Number of pages	4
Journal	Analytical Chemistry
Volume	58
Issue number	4
DOIs	https://doi.org/10.1021/ac00295a011
State	Published - Apr 1986

All Science Journal Classification (ASJC) codes

Analytical Chemistry

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10.1021/ac00295a011

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abstract = "An apparatus is described for the automation of the first part of a proven method for part-per-trillion dioxin analysis. A microprocessor controls the valves and solvent flow for the sequential extraction and enrichment of five tissue samples over a 20-h period. Sample and solvent selection for the multicolumn system and reversed flow elution, fraction collection, and column regeneration are all accomplished without operator attention. The time required by the analyst per sample has been reduced 50% compared with the totally manual method, resulting in greater throughput and lower personnel costs. The apparatus can be easily assembled with commercially available components.",

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AU - Liddle, John A.

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AB - An apparatus is described for the automation of the first part of a proven method for part-per-trillion dioxin analysis. A microprocessor controls the valves and solvent flow for the sequential extraction and enrichment of five tissue samples over a 20-h period. Sample and solvent selection for the multicolumn system and reversed flow elution, fraction collection, and column regeneration are all accomplished without operator attention. The time required by the analyst per sample has been reduced 50% compared with the totally manual method, resulting in greater throughput and lower personnel costs. The apparatus can be easily assembled with commercially available components.

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Automated Apparatus for the Extraction and Enrichment of 2,3,7,8-Tetrachlorodibenzo-p-dioxin in Human Adipose Tissue

Abstract

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