@inproceedings{5c2b78f93ba648009bb527a664c3c28a,
title = "Automated Ventricle Parcellation and Evan's Ratio Computation in Pre- and Post-Surgical Ventriculomegaly",
abstract = "Normal pressure hydrocephalus (NPH) is a brain disorder associated with enlarged ventricles and multiple cognitive and motor symptoms. The degree of ventricular enlargement can be measured using magnetic resonance images (MRIs) and characterized quantitatively using the Evan's ratio (ER). Automatic computation of ER is desired to avoid the extra time and variations associated with manual measurements on MRI. Because shunt surgery is often used to treat NPH, it is necessary that this process be robust to image artifacts caused by the shunt and related implants. In this paper, we propose a 3D regions-of-interest aware (ROI-aware) network for segmenting the ventricles. The method achieves state-of-the-art performance on both pre-surgery MRIs and post-surgery MRIs with artifacts. Based on our segmentation results, we also describe an automated approach to compute ER from these results. Experimental results on multiple datasets demonstrate the potential of the proposed method to assist clinicians in the diagnosis and management of NPH.",
author = "Yuli Wang and Anqi Feng and Yuan Xue and Lianrui Zuo and Yihao Liu and Blitz, {Ari M.} and Luciano, {Mark G.} and Aaron Carass and Prince, {Jerry L.}",
note = "Publisher Copyright: {\textcopyright} 2023 IEEE.; 20th IEEE International Symposium on Biomedical Imaging, ISBI 2023 ; Conference date: 18-04-2023 Through 21-04-2023",
year = "2023",
doi = "10.1109/ISBI53787.2023.10230729",
language = "English (US)",
series = "Proceedings - International Symposium on Biomedical Imaging",
publisher = "IEEE Computer Society",
booktitle = "2023 IEEE International Symposium on Biomedical Imaging, ISBI 2023",
address = "United States",
}