Abstract
An autoregulated pulsed-DC iontophoretic device with slow turn-on current has been developed. A specialized high-frequency pulse with a duty cycle of 50% or less is used which will reduce skin irritation due to polarization effects. To avoid patient discomfort, current delivery is increased gradually over a two-minute period to allow the skin to adapt to the applied current level. The rate of drug delivery is regulated by controlling the energy of the delivered pulse. For antihypertensive-drug administration, the device has the arterial pressure and continually readjusts delivery rates to keep it close to a desired target value.
| Original language | English (US) |
|---|---|
| Pages | 51-52 |
| Number of pages | 2 |
| State | Published - Dec 1 1989 |
| Event | Proceedings of the Fifteenth Annual Northeast Bioengineering Conference - Boston, MA, USA Duration: Mar 27 1989 → Mar 28 1989 |
Other
| Other | Proceedings of the Fifteenth Annual Northeast Bioengineering Conference |
|---|---|
| City | Boston, MA, USA |
| Period | 3/27/89 → 3/28/89 |
All Science Journal Classification (ASJC) codes
- Bioengineering