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Azaxanthene based selective glucocorticoid receptor modulators: Design, synthesis, and pharmacological evaluation of (S)-4-(5-(1-((1,3,4-Thiadiazol-2- yl)amino)-2-methyl-1-oxopropan-2-yl)-5 H-chromeno[2,3-b]pyridin-2-yl)-2-fluoro- N, N-dimethylbenzamide (BMS-776532) and its methylene homologue (BMS-791826)

  • David S. Weinstein
  • , Hua Gong
  • , Arthur M. Doweyko
  • , Mark Cunningham
  • , Sium Habte
  • , Jin Hong Wang
  • , Deborah A. Holloway
  • , Christine Burke
  • , Ling Gao
  • , Victor Guarino
  • , Julie Carman
  • , John E. Somerville
  • , David Shuster
  • , Luisa Salter-Cid
  • , John H. Dodd
  • , Steven G. Nadler
  • , Joel C. Barrish

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Pharmacology, Toxicology and Pharmaceutical Science

Biochemistry, Genetics and Molecular Biology