@article{2e83e9afae4b4da08f08f8b9bbc6c626,
title = "B-Cell-Intrinsic Type 1 Interferon Signaling Is Crucial for Loss of Tolerance and the Development of Autoreactive B Cells",
abstract = "The B-cell-intrinsic mechanisms of type 1 interferon (T1IFN) signaling in regulating B cell tolerance is unclear. Domeier et al. show that T1IFN signaling in B cells causes loss of B cell tolerance, promoting autoreactive B cell development into the antibody-forming cell and germinal center pathways by regulating BCR signaling.",
author = "Domeier, {Phillip P.} and Chodisetti, {Sathi Babu} and Schell, {Stephanie L.} and Yuka Imamura and Fasnacht, {Melinda J.} and Chetna Soni and Ziaur Rahman",
note = "Funding Information: We thank Dr. Aron Lukacher and Adam J. Fike for the critical reading of the manuscript. We also thank the PSUHMC flow cytometry core facility for their assistance. This work was supported by the NIH grants RO1A1091670 to Z.S.M.R. and 5F31AI122608 to P.D. ",
year = "2018",
month = jul,
day = "10",
doi = "10.1016/j.celrep.2018.06.046",
language = "English (US)",
volume = "24",
pages = "406--418",
journal = "Cell Reports",
issn = "2211-1247",
publisher = "Cell Press",
number = "2",
}