TY - JOUR
T1 - Bacillus Calmette-Guerin injections for melanoma immunotherapy
T2 - Potential for a false-positive PET/CT
AU - Sogge, Steven M.
AU - Fotos, Joseph S.
AU - Tulchinsky, Mark
N1 - Publisher Copyright:
Copyright © 2015 Wolters Kluwer Health, Inc. All rights reserved.
PY - 2015/4/21
Y1 - 2015/4/21
N2 - An 82-year-old woman presented for routine follow-up PET/CT after undergoing local melanoma resection in the left lower leg, isolated limb infusion chemotherapy, and immunomodulation therapy with Bacillus Calmette-Guérin (BCG) vaccine. Symmetric, bilateral, moderately intense FDG avid axillary and inguinal cutaneous nodules were observed that were new from the prior PETCT. The patient had developed skin lesions at the BCG injection sites several months before the study. The case raises awareness to PET/CT appearance of local inflammatory response to BCG injection, which could be mistaken by an unaware reader for recurrent melanoma.
AB - An 82-year-old woman presented for routine follow-up PET/CT after undergoing local melanoma resection in the left lower leg, isolated limb infusion chemotherapy, and immunomodulation therapy with Bacillus Calmette-Guérin (BCG) vaccine. Symmetric, bilateral, moderately intense FDG avid axillary and inguinal cutaneous nodules were observed that were new from the prior PETCT. The patient had developed skin lesions at the BCG injection sites several months before the study. The case raises awareness to PET/CT appearance of local inflammatory response to BCG injection, which could be mistaken by an unaware reader for recurrent melanoma.
UR - http://www.scopus.com/inward/record.url?scp=84925446309&partnerID=8YFLogxK
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U2 - 10.1097/RLU.0000000000000718
DO - 10.1097/RLU.0000000000000718
M3 - Article
C2 - 25674877
AN - SCOPUS:84925446309
SN - 0363-9762
VL - 40
SP - 368
EP - 369
JO - Clinical nuclear medicine
JF - Clinical nuclear medicine
IS - 4
ER -
