TY - JOUR
T1 - Background levels of non-ortho-substituted (coplanar) polychlorinated biphenyls in human serum of Missouri residents
AU - Shadel, B. N.
AU - Evans, R. G.
AU - Roberts, D.
AU - Clardy, S.
AU - Jordan-Izaguirre, D.
AU - Patterson, D. G.
AU - Needham, L. L.
N1 - Funding Information:
This report was supported in part by funds from the Comprehensive Environmental Response, Compensation, and Liability Act trust fund provided to the Missouri Department of Health, under Grant No. H75/ATH781507 from the Agency for Toxic Substances and Disease Registry, Public Health Service, US Department of Health and Human Services.
PY - 2001
Y1 - 2001
N2 - This study characterizes the levels of polychlorinated biphenyls (PCB) congeners PCB 77, PCB 81, PCB 126, and PCB 169, in a group of 150 men and women with no documented exposure to PCBs. Its purpose is to provide current referent levels of coplanar PCBs in Missouri residents and to compare those levels to levels reported in the literature from the United States and other countries. Although this study used an extensive questionnaire assessing potential sources of exposure, no positive relations were found between these exposure sources and participants' PCB levels. The PCB levels for the four congeners measured were lower than any reported in the literature. PCBs 126 and 169 are only two of the dioxin-like congeners; however, their contribution makes up 11% of the total TEQ. Age was significantly related to PCB 126 and PCB 169. For every one-year increase in age, both PCB congeners increased by approximately 0.4 parts per trillion (ppt). There was no gender difference for PCB 126; however, PCB 169 levels were 3 ppt higher in males than females.
AB - This study characterizes the levels of polychlorinated biphenyls (PCB) congeners PCB 77, PCB 81, PCB 126, and PCB 169, in a group of 150 men and women with no documented exposure to PCBs. Its purpose is to provide current referent levels of coplanar PCBs in Missouri residents and to compare those levels to levels reported in the literature from the United States and other countries. Although this study used an extensive questionnaire assessing potential sources of exposure, no positive relations were found between these exposure sources and participants' PCB levels. The PCB levels for the four congeners measured were lower than any reported in the literature. PCBs 126 and 169 are only two of the dioxin-like congeners; however, their contribution makes up 11% of the total TEQ. Age was significantly related to PCB 126 and PCB 169. For every one-year increase in age, both PCB congeners increased by approximately 0.4 parts per trillion (ppt). There was no gender difference for PCB 126; however, PCB 169 levels were 3 ppt higher in males than females.
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U2 - 10.1016/S0045-6535(00)00457-4
DO - 10.1016/S0045-6535(00)00457-4
M3 - Article
C2 - 11372890
AN - SCOPUS:0035041430
SN - 0045-6535
VL - 43
SP - 967
EP - 976
JO - Chemosphere
JF - Chemosphere
IS - 4-7
ER -