Bacterial RNA polymerases: The wholo story

Katsuhiko S. Murakami, Seth A. Darst

Research output: Contribution to journalReview articlepeer-review

399 Scopus citations


Recent structural and biophysical results have provided unprecedented insights into the structure and function of the bacterial RNA polymerase holoenzyme as it goes through the steps of transcription initiation. Comparisons with structural analyses of evolutionarily unrelated RNA polymerases reveal unexpected general features of the initiation process.

Original languageEnglish (US)
Pages (from-to)31-39
Number of pages9
JournalCurrent Opinion in Structural Biology
Issue number1
StatePublished - Feb 1 2003

All Science Journal Classification (ASJC) codes

  • Structural Biology
  • Molecular Biology


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