Bacterial RNA polymerases: The wholo story

Katsuhiko S. Murakami; Seth A. Darst

doi:10.1016/S0959-440X(02)00005-2

Bacterial RNA polymerases: The wholo story

Katsuhiko S. Murakami
, Seth A. Darst

Research output: Contribution to journal › Review article › peer-review

417 Scopus citations

Abstract

Recent structural and biophysical results have provided unprecedented insights into the structure and function of the bacterial RNA polymerase holoenzyme as it goes through the steps of transcription initiation. Comparisons with structural analyses of evolutionarily unrelated RNA polymerases reveal unexpected general features of the initiation process.

Original language	English (US)
Pages (from-to)	31-39
Number of pages	9
Journal	Current Opinion in Structural Biology
Volume	13
Issue number	1
DOIs	https://doi.org/10.1016/S0959-440X(02)00005-2
State	Published - Feb 1 2003

All Science Journal Classification (ASJC) codes

Structural Biology
Molecular Biology

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10.1016/S0959-440X(02)00005-2

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title = "Bacterial RNA polymerases: The wholo story",

abstract = "Recent structural and biophysical results have provided unprecedented insights into the structure and function of the bacterial RNA polymerase holoenzyme as it goes through the steps of transcription initiation. Comparisons with structural analyses of evolutionarily unrelated RNA polymerases reveal unexpected general features of the initiation process.",

author = "Murakami, \{Katsuhiko S.\} and Darst, \{Seth A.\}",

note = "Funding Information: We thank past and present members of the Darst Laboratory, and our many collaborators in the field of prokaryotic transcription, including the laboratories of Alex Goldfarb, Carol Gross, Ann Hochschild, Robert Landick, Jeff Roberts and Konstantin Severinov for their many contributions. Work in the Darst laboratory was funded by the National Institutes of Health. ",

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T2 - The wholo story

AU - Murakami, Katsuhiko S.

AU - Darst, Seth A.

N1 - Funding Information: We thank past and present members of the Darst Laboratory, and our many collaborators in the field of prokaryotic transcription, including the laboratories of Alex Goldfarb, Carol Gross, Ann Hochschild, Robert Landick, Jeff Roberts and Konstantin Severinov for their many contributions. Work in the Darst laboratory was funded by the National Institutes of Health.

PY - 2003/2/1

Y1 - 2003/2/1

N2 - Recent structural and biophysical results have provided unprecedented insights into the structure and function of the bacterial RNA polymerase holoenzyme as it goes through the steps of transcription initiation. Comparisons with structural analyses of evolutionarily unrelated RNA polymerases reveal unexpected general features of the initiation process.

AB - Recent structural and biophysical results have provided unprecedented insights into the structure and function of the bacterial RNA polymerase holoenzyme as it goes through the steps of transcription initiation. Comparisons with structural analyses of evolutionarily unrelated RNA polymerases reveal unexpected general features of the initiation process.

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UR - https://www.scopus.com/pages/publications/0037308665#tab=citedBy

U2 - 10.1016/S0959-440X(02)00005-2

DO - 10.1016/S0959-440X(02)00005-2

M3 - Review article

C2 - 12581657

AN - SCOPUS:0037308665

SN - 0959-440X

VL - 13

SP - 31

EP - 39

JO - Current Opinion in Structural Biology

JF - Current Opinion in Structural Biology

IS - 1

ER -

Bacterial RNA polymerases: The wholo story

Abstract

All Science Journal Classification (ASJC) codes

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