Barrett’s Esophagus Surveillance: WATS, Real-Time Endoscopic Microscopy

Joshua Winder; Eric M. Pauli

doi:10.1007/978-3-031-21044-0_15

Barrett’s Esophagus Surveillance: WATS, Real-Time Endoscopic Microscopy

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

Endoscopic screening and surveillance of Barrett’s esophagus (BE) are limited to the small volume of tissue sampled by random biopsies, leaving a large area of metaplasia that may contain unidentified dysplasia. Technologies to better assess the mucosa and direct further examination or to better diagnose the severity of disease represent an evolution of the endoscopic surveillance of BE. Wide-area transepithelial sampling of the esophagus with computer-assisted three-dimensional analysis (WATS^3D) and endoscopic microscopy including confocal laser endomicroscopy (CLE) or optical coherence tomography (OTC) may improve the ability to diagnose and manage patients with BE. In this chapter, we will review these emerging technologies, their application, and the clinical evidence behind their use.

Original language	English (US)
Title of host publication	The SAGES Manual Operating through the Endoscope, Second Edition
Publisher	Springer International Publishing
Pages	315-327
Number of pages	13
ISBN (Electronic)	9783031210440
ISBN (Print)	9783031210433
DOIs	https://doi.org/10.1007/978-3-031-21044-0_15
State	Published - Jan 1 2023

All Science Journal Classification (ASJC) codes

General Medicine

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10.1007/978-3-031-21044-0_15

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AB - Endoscopic screening and surveillance of Barrett’s esophagus (BE) are limited to the small volume of tissue sampled by random biopsies, leaving a large area of metaplasia that may contain unidentified dysplasia. Technologies to better assess the mucosa and direct further examination or to better diagnose the severity of disease represent an evolution of the endoscopic surveillance of BE. Wide-area transepithelial sampling of the esophagus with computer-assisted three-dimensional analysis (WATS3D) and endoscopic microscopy including confocal laser endomicroscopy (CLE) or optical coherence tomography (OTC) may improve the ability to diagnose and manage patients with BE. In this chapter, we will review these emerging technologies, their application, and the clinical evidence behind their use.

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Barrett’s Esophagus Surveillance: WATS, Real-Time Endoscopic Microscopy

Abstract

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