Barrett’s Esophagus Surveillance: WATS, Real-Time Endoscopic Microscopy

Research output: Chapter in Book/Report/Conference proceedingChapter


Endoscopic screening and surveillance of Barrett’s esophagus (BE) are limited to the small volume of tissue sampled by random biopsies, leaving a large area of metaplasia that may contain unidentified dysplasia. Technologies to better assess the mucosa and direct further examination or to better diagnose the severity of disease represent an evolution of the endoscopic surveillance of BE. Wide-area transepithelial sampling of the esophagus with computer-assisted three-dimensional analysis (WATS3D) and endoscopic microscopy including confocal laser endomicroscopy (CLE) or optical coherence tomography (OTC) may improve the ability to diagnose and manage patients with BE. In this chapter, we will review these emerging technologies, their application, and the clinical evidence behind their use.

Original languageEnglish (US)
Title of host publicationThe SAGES Manual Operating through the Endoscope, Second Edition
PublisherSpringer International Publishing
Number of pages13
ISBN (Electronic)9783031210440
ISBN (Print)9783031210433
StatePublished - Jan 1 2023

All Science Journal Classification (ASJC) codes

  • General Medicine

Cite this