Endoscopic screening and surveillance of Barrett’s esophagus (BE) are limited to the small volume of tissue sampled by random biopsies, leaving a large area of metaplasia that may contain unidentified dysplasia. Technologies to better assess the mucosa and direct further examination or to better diagnose the severity of disease represent an evolution of the endoscopic surveillance of BE. Wide-area transepithelial sampling of the esophagus with computer-assisted three-dimensional analysis (WATS3D) and endoscopic microscopy including confocal laser endomicroscopy (CLE) or optical coherence tomography (OTC) may improve the ability to diagnose and manage patients with BE. In this chapter, we will review these emerging technologies, their application, and the clinical evidence behind their use.
|Title of host publication
|The SAGES Manual Operating through the Endoscope, Second Edition
|Springer International Publishing
|Number of pages
|Published - Jan 1 2023
All Science Journal Classification (ASJC) codes
- General Medicine