TY - JOUR
T1 - Battleground Zero
T2 - A Review of Best Practice Recommendations for Clostridioides (Clostridium) difficile Testing
AU - Bobenchik, April M.
N1 - Publisher Copyright:
© 2019 Elsevier Ltd
PY - 2019/10/15
Y1 - 2019/10/15
N2 - Diagnosing Clostridioides (formerly Clostridium) difficile infection can be difficult, especially when there is a lack of consensus in the definition, disagreement on the gold standard, and indecision as to which is the best testing method. As laboratorians, we look to published best practice documents for guidance, but oftentimes, the recommendations are not straightforward. This article reviews the most recent guidance documents published by the Infectious Diseases Society of America/Society of Healthcare Epidemiology of America, the American College of Gastroenterology, the European Society of Clinical Microbiology and Infectious Diseases, and the American Society for Microbiology. Recommendations for the desired testing population, most accurate diagnostic test or testing algorithm, and frequency of testing are compared between the societies. A review of the guidance methodologies is provided, and strategies for laboratory adoption are discussed.
AB - Diagnosing Clostridioides (formerly Clostridium) difficile infection can be difficult, especially when there is a lack of consensus in the definition, disagreement on the gold standard, and indecision as to which is the best testing method. As laboratorians, we look to published best practice documents for guidance, but oftentimes, the recommendations are not straightforward. This article reviews the most recent guidance documents published by the Infectious Diseases Society of America/Society of Healthcare Epidemiology of America, the American College of Gastroenterology, the European Society of Clinical Microbiology and Infectious Diseases, and the American Society for Microbiology. Recommendations for the desired testing population, most accurate diagnostic test or testing algorithm, and frequency of testing are compared between the societies. A review of the guidance methodologies is provided, and strategies for laboratory adoption are discussed.
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U2 - 10.1016/j.clinmicnews.2019.09.002
DO - 10.1016/j.clinmicnews.2019.09.002
M3 - Article
AN - SCOPUS:85072853727
SN - 0196-4399
VL - 41
SP - 175
EP - 183
JO - Clinical Microbiology Newsletter
JF - Clinical Microbiology Newsletter
IS - 20
ER -