TY - JOUR
T1 - Behavior problems among cocaine exposed children
T2 - Role of physiological regulation and parenting
AU - Finger, Brent
AU - Schuetze, Pamela
AU - Eiden, Rina D.
N1 - Funding Information:
The authors thank the families who participated in this study and the research staff responsible for data collection. Special thanks to Dr. Claire Coles for her collaboration on the larger study, Dr. Amol Lele for her collaboration on data collection at the Women and Children's Hospital of Buffalo, and Dr. Michael Ray for his collaboration on data collection at the Sisters of Charity Hospital of Buffalo. Research reported in this publication was supported by the National Institute on Drug Abuse of the National Institutes of Health under award number R01DA013190 . The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health.
PY - 2014/3
Y1 - 2014/3
N2 - This study examined interrelations between prenatal cocaine exposure, child autonomic regulation, parenting behavior and child sex on parent-reported behavior problems at 36. months of age. We hypothesized that respiratory sinus arrhythmia (RSA) at 13. months of age would mediate the relation between cocaine exposure and behavior problems. We also hypothesized that child sex, maternal negative affect, and maternal sensitivity observed at 13. months of age would moderate the relation between RSA and behavior problems. Results revealed that cocaine exposure predicted low baseline RSA and low RSA withdrawal during a negative affect task. Low baseline RSA, in turn, predicted fewer behavior problems offering support for an indirect association between cocaine exposure and behavior problems. The association between baseline RSA and behavior problems was further moderated by maternal negative affect such that high baseline RSA was more strongly related to behavior problems under conditions of high compared to low maternal negative affect. Results also revealed a near significant trend for baseline RSA to be more strongly related to behavior problems among boys than girls. These findings highlight several possible pathways toward behavior problems among cocaine exposed children.
AB - This study examined interrelations between prenatal cocaine exposure, child autonomic regulation, parenting behavior and child sex on parent-reported behavior problems at 36. months of age. We hypothesized that respiratory sinus arrhythmia (RSA) at 13. months of age would mediate the relation between cocaine exposure and behavior problems. We also hypothesized that child sex, maternal negative affect, and maternal sensitivity observed at 13. months of age would moderate the relation between RSA and behavior problems. Results revealed that cocaine exposure predicted low baseline RSA and low RSA withdrawal during a negative affect task. Low baseline RSA, in turn, predicted fewer behavior problems offering support for an indirect association between cocaine exposure and behavior problems. The association between baseline RSA and behavior problems was further moderated by maternal negative affect such that high baseline RSA was more strongly related to behavior problems under conditions of high compared to low maternal negative affect. Results also revealed a near significant trend for baseline RSA to be more strongly related to behavior problems among boys than girls. These findings highlight several possible pathways toward behavior problems among cocaine exposed children.
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U2 - 10.1016/j.ntt.2014.01.001
DO - 10.1016/j.ntt.2014.01.001
M3 - Article
C2 - 24480789
AN - SCOPUS:84896698122
SN - 0892-0362
VL - 42
SP - 51
EP - 59
JO - Neurotoxicology and Teratology
JF - Neurotoxicology and Teratology
ER -