TY - JOUR
T1 - Benign Lymphocytic Infiltrate of the Skin
T2 - Correlation of Clinical and Pathologic Findings
AU - Helm, Klaus
AU - MULLER, SIGFRID A.
PY - 1992
Y1 - 1992
N2 - In a retrospective study of 137 biopsy specimens of skin from 137 patients (69 men and 68 women) that had been obtained between 1972 and 1989 at our institution and that had perivascular and periappendageal lymphocytic infiltrates characteristic of those described as benign lymphocytic infiltrate (BLI), we determined the specificity of the histologic diagnosis and the correlation with clinical data. The final diagnoses, based on clinical and laboratory data and histologic findings, were BLI (59), possible BLI (7), lupus erythematosus (LE) (12), possible LE (7), procainamide-induced LE (1), insect bites (9), possible insect bites (3), polymorphous light eruption (4), lymphocytoma (4), urticaria (4), and indeterminate or miscellaneous diagnoses (27). BLI is a clinical and histologic syndrome that can be heterogeneous in origin. We recommend careful evaluation to exclude other disorders such as LE, polymorphous light eruption, lymphocytoma, and insect bites. Direct immunofluorescence microscopy and immunophenotypic studies may help distinguish BLI from LE.
AB - In a retrospective study of 137 biopsy specimens of skin from 137 patients (69 men and 68 women) that had been obtained between 1972 and 1989 at our institution and that had perivascular and periappendageal lymphocytic infiltrates characteristic of those described as benign lymphocytic infiltrate (BLI), we determined the specificity of the histologic diagnosis and the correlation with clinical data. The final diagnoses, based on clinical and laboratory data and histologic findings, were BLI (59), possible BLI (7), lupus erythematosus (LE) (12), possible LE (7), procainamide-induced LE (1), insect bites (9), possible insect bites (3), polymorphous light eruption (4), lymphocytoma (4), urticaria (4), and indeterminate or miscellaneous diagnoses (27). BLI is a clinical and histologic syndrome that can be heterogeneous in origin. We recommend careful evaluation to exclude other disorders such as LE, polymorphous light eruption, lymphocytoma, and insect bites. Direct immunofluorescence microscopy and immunophenotypic studies may help distinguish BLI from LE.
UR - http://www.scopus.com/inward/record.url?scp=0026773448&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0026773448&partnerID=8YFLogxK
U2 - 10.1016/S0025-6196(12)60799-X
DO - 10.1016/S0025-6196(12)60799-X
M3 - Article
C2 - 1434913
AN - SCOPUS:0026773448
SN - 0025-6196
VL - 67
SP - 748
EP - 754
JO - Mayo Clinic Proceedings
JF - Mayo Clinic Proceedings
IS - 8
ER -