Benign Transient Hyperphosphatasemia Associated With Epstein-Barr Virus Enteritis in a Pediatric Liver Transplant Patient: A Case Report

T. Hranjec; H. Bonatti; A. L. Roman; C. Sifri; S. M. Borowitz; B. H. Barnes; T. R. Flohr; T. L. Pruett; R. G. Sawyer; T. M. Schmitt

doi:10.1016/j.transproceed.2008.04.011

Benign Transient Hyperphosphatasemia Associated With Epstein-Barr Virus Enteritis in a Pediatric Liver Transplant Patient: A Case Report

T. Hranjec
, H. Bonatti
, A. L. Roman
, C. Sifri
, S. M. Borowitz
, B. H. Barnes
, T. R. Flohr
, T. L. Pruett
, R. G. Sawyer
, T. M. Schmitt

Research output: Contribution to journal › Article › peer-review

7 Scopus citations

Abstract

Transient hyperphosphatasemia was found in a 3-year-old male liver transplant recipient. The condition was associated with diarrheal disease due to the Epstein-Barr virus (EBV). Immunosuppression was tapered and valganciclovir prescribed for 3 months, after which the diarrhea resolved and the EBV polymerase chain reaction assays became negative. After 6 months, alkaline phosphatase levels normalized. Isolated elevation of alkaline phosphatase in conjunction with enteric infection is a rare condition. No further diagnostic or therapeutic interventions except treatment of the underlying infection are needed, as this has been shown to be a benign, transient condition.

Original language	English (US)
Pages (from-to)	1780-1782
Number of pages	3
Journal	Transplantation proceedings
Volume	40
Issue number	5
DOIs	https://doi.org/10.1016/j.transproceed.2008.04.011
State	Published - Jun 2008

All Science Journal Classification (ASJC) codes

Surgery
Transplantation

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.transproceed.2008.04.011

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Hranjec, T., Bonatti, H., Roman, A. L., Sifri, C., Borowitz, S. M., Barnes, B. H., Flohr, T. R., Pruett, T. L., Sawyer, R. G., & Schmitt, T. M. (2008). Benign Transient Hyperphosphatasemia Associated With Epstein-Barr Virus Enteritis in a Pediatric Liver Transplant Patient: A Case Report. Transplantation proceedings, 40(5), 1780-1782. https://doi.org/10.1016/j.transproceed.2008.04.011

@article{772a160845fe456d901f7dfcfb6c1732,

title = "Benign Transient Hyperphosphatasemia Associated With Epstein-Barr Virus Enteritis in a Pediatric Liver Transplant Patient: A Case Report",

abstract = "Transient hyperphosphatasemia was found in a 3-year-old male liver transplant recipient. The condition was associated with diarrheal disease due to the Epstein-Barr virus (EBV). Immunosuppression was tapered and valganciclovir prescribed for 3 months, after which the diarrhea resolved and the EBV polymerase chain reaction assays became negative. After 6 months, alkaline phosphatase levels normalized. Isolated elevation of alkaline phosphatase in conjunction with enteric infection is a rare condition. No further diagnostic or therapeutic interventions except treatment of the underlying infection are needed, as this has been shown to be a benign, transient condition.",

author = "T. Hranjec and H. Bonatti and Roman, \{A. L.\} and C. Sifri and Borowitz, \{S. M.\} and Barnes, \{B. H.\} and Flohr, \{T. R.\} and Pruett, \{T. L.\} and Sawyer, \{R. G.\} and Schmitt, \{T. M.\}",

year = "2008",

month = jun,

doi = "10.1016/j.transproceed.2008.04.011",

language = "English (US)",

volume = "40",

pages = "1780--1782",

journal = "Transplantation proceedings",

issn = "0041-1345",

publisher = "Elsevier Inc.",

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}

Hranjec, T, Bonatti, H, Roman, AL, Sifri, C, Borowitz, SM, Barnes, BH, Flohr, TR, Pruett, TL, Sawyer, RG & Schmitt, TM 2008, 'Benign Transient Hyperphosphatasemia Associated With Epstein-Barr Virus Enteritis in a Pediatric Liver Transplant Patient: A Case Report', Transplantation proceedings, vol. 40, no. 5, pp. 1780-1782. https://doi.org/10.1016/j.transproceed.2008.04.011

TY - JOUR

T1 - Benign Transient Hyperphosphatasemia Associated With Epstein-Barr Virus Enteritis in a Pediatric Liver Transplant Patient

T2 - A Case Report

AU - Hranjec, T.

AU - Bonatti, H.

AU - Roman, A. L.

AU - Sifri, C.

AU - Borowitz, S. M.

AU - Barnes, B. H.

AU - Flohr, T. R.

AU - Pruett, T. L.

AU - Sawyer, R. G.

AU - Schmitt, T. M.

PY - 2008/6

Y1 - 2008/6

N2 - Transient hyperphosphatasemia was found in a 3-year-old male liver transplant recipient. The condition was associated with diarrheal disease due to the Epstein-Barr virus (EBV). Immunosuppression was tapered and valganciclovir prescribed for 3 months, after which the diarrhea resolved and the EBV polymerase chain reaction assays became negative. After 6 months, alkaline phosphatase levels normalized. Isolated elevation of alkaline phosphatase in conjunction with enteric infection is a rare condition. No further diagnostic or therapeutic interventions except treatment of the underlying infection are needed, as this has been shown to be a benign, transient condition.

AB - Transient hyperphosphatasemia was found in a 3-year-old male liver transplant recipient. The condition was associated with diarrheal disease due to the Epstein-Barr virus (EBV). Immunosuppression was tapered and valganciclovir prescribed for 3 months, after which the diarrhea resolved and the EBV polymerase chain reaction assays became negative. After 6 months, alkaline phosphatase levels normalized. Isolated elevation of alkaline phosphatase in conjunction with enteric infection is a rare condition. No further diagnostic or therapeutic interventions except treatment of the underlying infection are needed, as this has been shown to be a benign, transient condition.

UR - https://www.scopus.com/pages/publications/45449097664

UR - https://www.scopus.com/pages/publications/45449097664#tab=citedBy

U2 - 10.1016/j.transproceed.2008.04.011

DO - 10.1016/j.transproceed.2008.04.011

M3 - Article

C2 - 18589195

AN - SCOPUS:45449097664

SN - 0041-1345

VL - 40

SP - 1780

EP - 1782

JO - Transplantation proceedings

JF - Transplantation proceedings

IS - 5

ER -

Benign Transient Hyperphosphatasemia Associated With Epstein-Barr Virus Enteritis in a Pediatric Liver Transplant Patient: A Case Report

Abstract

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