Benzodiazepine toxicity with profound suppression of the electroencephalogram

Jason P. Stabley; Edward J. Frear; Marvis Wine; Milind J. Kothari

Benzodiazepine toxicity with profound suppression of the electroencephalogram

Jason P. Stabley, Edward J. Frear, Marvis Wine, Milind J. Kothari

Research output: Contribution to journal › Article › peer-review

Abstract

The authors report the case of a 60-year-old man with respiratory distress secondary to exacerbation of chronic obstructive pulmonary disease, right lower lobe pneumonia, and severe bronchospasm. High doses of lorazepam were given intravenously after failure to control bronchospasm and agitation with bronchodilators and mucolytic agents; the patient was unresponsive to all stimuli while receiving lorazepam. Electroencephalography revealed a profoundly suppressed pattern without accompanying low-voltage fast activity - this was reversible following withdrawal of the lorazepam.

Original language	English (US)
Pages (from-to)	435-436
Number of pages	2
Journal	Journal of the American Osteopathic Association
Volume	100
Issue number	7
State	Published - Jul 2000

All Science Journal Classification (ASJC) codes

Complementary and alternative medicine

Cite this

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title = "Benzodiazepine toxicity with profound suppression of the electroencephalogram",

abstract = "The authors report the case of a 60-year-old man with respiratory distress secondary to exacerbation of chronic obstructive pulmonary disease, right lower lobe pneumonia, and severe bronchospasm. High doses of lorazepam were given intravenously after failure to control bronchospasm and agitation with bronchodilators and mucolytic agents; the patient was unresponsive to all stimuli while receiving lorazepam. Electroencephalography revealed a profoundly suppressed pattern without accompanying low-voltage fast activity - this was reversible following withdrawal of the lorazepam.",

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N2 - The authors report the case of a 60-year-old man with respiratory distress secondary to exacerbation of chronic obstructive pulmonary disease, right lower lobe pneumonia, and severe bronchospasm. High doses of lorazepam were given intravenously after failure to control bronchospasm and agitation with bronchodilators and mucolytic agents; the patient was unresponsive to all stimuli while receiving lorazepam. Electroencephalography revealed a profoundly suppressed pattern without accompanying low-voltage fast activity - this was reversible following withdrawal of the lorazepam.

AB - The authors report the case of a 60-year-old man with respiratory distress secondary to exacerbation of chronic obstructive pulmonary disease, right lower lobe pneumonia, and severe bronchospasm. High doses of lorazepam were given intravenously after failure to control bronchospasm and agitation with bronchodilators and mucolytic agents; the patient was unresponsive to all stimuli while receiving lorazepam. Electroencephalography revealed a profoundly suppressed pattern without accompanying low-voltage fast activity - this was reversible following withdrawal of the lorazepam.

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Benzodiazepine toxicity with profound suppression of the electroencephalogram

Abstract

All Science Journal Classification (ASJC) codes

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