Beyond Purple Hearts: A Colorful Approach to Isolate Distinct Heart Cells from Human iPSCs

Lauren N. Randolph; Xiaojun Lance Lian

doi:10.1016/j.stem.2019.04.003

Beyond Purple Hearts: A Colorful Approach to Isolate Distinct Heart Cells from Human iPSCs

Lauren N. Randolph
, Xiaojun Lance Lian

Research output: Contribution to journal › Short survey › peer-review

1 Scopus citations

Abstract

In this issue of Cell Stem Cell, Zhang et al. (2019)describe a double-reporter iPSC line based on the expression of key cardiac transcription factors, TBX5 and NKX2.5, that delineates cardiac lineage specification in vitro and enables isolation of relatively pure chamber-specific cardiomyocytes, which are critical for drug screening, tissue engineering, and disease modeling.

Original language	English (US)
Pages (from-to)	675-677
Number of pages	3
Journal	Cell Stem Cell
Volume	24
Issue number	5
DOIs	https://doi.org/10.1016/j.stem.2019.04.003
State	Published - May 2 2019

All Science Journal Classification (ASJC) codes

Molecular Medicine
Genetics
Cell Biology

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10.1016/j.stem.2019.04.003

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title = "Beyond Purple Hearts: A Colorful Approach to Isolate Distinct Heart Cells from Human iPSCs",

abstract = "In this issue of Cell Stem Cell, Zhang et al. (2019)describe a double-reporter iPSC line based on the expression of key cardiac transcription factors, TBX5 and NKX2.5, that delineates cardiac lineage specification in vitro and enables isolation of relatively pure chamber-specific cardiomyocytes, which are critical for drug screening, tissue engineering, and disease modeling.",

author = "Randolph, \{Lauren N.\} and Lian, \{Xiaojun Lance\}",

note = "Publisher Copyright: {\textcopyright} 2019 Elsevier Inc.",

year = "2019",

month = may,

day = "2",

doi = "10.1016/j.stem.2019.04.003",

language = "English (US)",

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journal = "Cell Stem Cell",

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T2 - A Colorful Approach to Isolate Distinct Heart Cells from Human iPSCs

AU - Randolph, Lauren N.

AU - Lian, Xiaojun Lance

PY - 2019/5/2

Y1 - 2019/5/2

N2 - In this issue of Cell Stem Cell, Zhang et al. (2019)describe a double-reporter iPSC line based on the expression of key cardiac transcription factors, TBX5 and NKX2.5, that delineates cardiac lineage specification in vitro and enables isolation of relatively pure chamber-specific cardiomyocytes, which are critical for drug screening, tissue engineering, and disease modeling.

AB - In this issue of Cell Stem Cell, Zhang et al. (2019)describe a double-reporter iPSC line based on the expression of key cardiac transcription factors, TBX5 and NKX2.5, that delineates cardiac lineage specification in vitro and enables isolation of relatively pure chamber-specific cardiomyocytes, which are critical for drug screening, tissue engineering, and disease modeling.

UR - https://www.scopus.com/pages/publications/85063934656

UR - https://www.scopus.com/pages/publications/85063934656#tab=citedBy

U2 - 10.1016/j.stem.2019.04.003

DO - 10.1016/j.stem.2019.04.003

M3 - Short survey

C2 - 31051127

AN - SCOPUS:85063934656

SN - 1934-5909

VL - 24

SP - 675

EP - 677

JO - Cell Stem Cell

JF - Cell Stem Cell

IS - 5

ER -

Beyond Purple Hearts: A Colorful Approach to Isolate Distinct Heart Cells from Human iPSCs

Abstract

All Science Journal Classification (ASJC) codes

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