Beyond translation: elongation factor-1α and the cytoskeleton

N. A. Durso, R. J. Cyr

Research output: Contribution to journalReview articlepeer-review

53 Scopus citations


While reported interactions of elongation factor-1α (EF-1α) with various other molecules involved in protein biosynthesis are abundant, its interactions with major cytoskeletal proteins have not been as extensively examined. Major roles for EF-1α in cytoskeletal organization emerge from a review of such interactions within species as diverse as slime molds and mammals, sea urchins and higher plants. Based on these studies, the integration of EF-1α's cytoskeletal roles with those of translation is considered, and prospective mechanisms for regulation of EF-1α's cytoskeletal associations are discussed.

Original languageEnglish (US)
Pages (from-to)99-105
Number of pages7
Issue number3-4
StatePublished - Sep 1994

All Science Journal Classification (ASJC) codes

  • Plant Science
  • Cell Biology


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