Bidirectional Homeostatic Regulation of a Depression-Related Brain State by Gamma-Aminobutyric Acidergic Deficits and Ketamine Treatment

Keyphrases

• Ketamine 100%
• γ-aminobutyric 100%
• Homeostatic Regulation 100%
• Brain State 100%
• Major Depressive Disorder 75%
• Medial Prefrontal Cortex (mPFC) 75%
• Hippocampus 50%
• Antidepressants 50%
• GABAergic Synapse 50%
• Surface Expression 50%
• Glutamatergic Transmission 50%
• Subanesthetic Dose 50%
• N-methyl-D-aspartate 50%
• GABAergic Dysfunction 50%
• Methyl 25%
• Construct Validity 25%
• Glutamatergic 25%
• Synapse 25%
• Glutamate Receptors 25%
• Wild Mice 25%
• Receptor Expression 25%
• Functional Impairment 25%
• Behavioral Consequences 25%
• Amino 25%
• GABAA Receptor (GABAAR) 25%
• Glutamatergic Synaptic Transmission 25%
• GABAergic 25%
• Predictive Validity 25%
• Glutamatergic Synapse 25%
• Propionic Acid 25%
• Acute Dose 25%
• Receptor 2 25%
• Potentiation 25%
• Functional Deficits 25%
• γ-aminobutyric Acid 25%
• Depressive-like Behavior 25%
• Synaptic Function 25%
• GABAergic Synaptic Transmission 25%

Neuroscience

• Ketamine 100%
• Synapse 80%
• Prefrontal Cortex 60%
• Glutamate Receptor 60%
• Major Depressive Disorder 60%
• AMPA 60%
• Hippocampus 40%
• Aspartic Acid 40%
• Synaptic Transmission 40%
• Antidepressant 40%
• Face 20%
• Receptor Expression 20%
• GABAA Receptor 20%
• Gamma-Aminobutyric Acid 20%