TY - JOUR
T1 - Biliary dyskinesia in the pediatric population
AU - Schermerhorn, Sophia MV
AU - Kulaylat, Afif N.
AU - Lucas, Donald J.
N1 - Publisher Copyright:
© 2025
PY - 2025/8
Y1 - 2025/8
N2 - Biliary dyskinesia (BD) is a functional gallbladder disorder increasingly diagnosed in pediatric patients and a leading indication for laparoscopic cholecystectomy (LC). The pathophysiology remains unclear despite its prevalence, with gallbladder dysmotility and inflammation implicated. Diagnostic challenges arise from a lack of validated pediatric criteria and inconsistent hepatobiliary iminodiacetic acid (HIDA) scan technique and interpretation. LC is effective for symptom resolution with low complication rates, but medical management, including proton pump inhibitors, demonstrates variable success. This review highlights the need for prospective studies to refine diagnostic criteria, identify predictors of treatment success, and compare treatment strategies to improve outcomes for children with BD.
AB - Biliary dyskinesia (BD) is a functional gallbladder disorder increasingly diagnosed in pediatric patients and a leading indication for laparoscopic cholecystectomy (LC). The pathophysiology remains unclear despite its prevalence, with gallbladder dysmotility and inflammation implicated. Diagnostic challenges arise from a lack of validated pediatric criteria and inconsistent hepatobiliary iminodiacetic acid (HIDA) scan technique and interpretation. LC is effective for symptom resolution with low complication rates, but medical management, including proton pump inhibitors, demonstrates variable success. This review highlights the need for prospective studies to refine diagnostic criteria, identify predictors of treatment success, and compare treatment strategies to improve outcomes for children with BD.
UR - https://www.scopus.com/pages/publications/105009753291
UR - https://www.scopus.com/inward/citedby.url?scp=105009753291&partnerID=8YFLogxK
U2 - 10.1016/j.sempedsurg.2025.151503
DO - 10.1016/j.sempedsurg.2025.151503
M3 - Article
C2 - 40618556
AN - SCOPUS:105009753291
SN - 1055-8586
VL - 34
JO - Seminars in pediatric surgery
JF - Seminars in pediatric surgery
M1 - 151503
ER -