BioBin: A bioinformatics tool for automating the binning of rare variants using publicly available biological knowledge

Keyphrases

• Publicly Available 100%
• Rare Variants 100%
• Biological Knowledge 100%
• Bioinformatics Tools 100%
• Gene Ontology 66%
• 1000 Genomes Project 66%
• Low-frequency Variants 66%
• Yoruba 66%
• Evolutionary Conserved Regions 66%
• Biotechnology 33%
• Signal Transduction Pathway 33%
• Genome Sequencing 33%
• Simulation Study 33%
• Complex Disease 33%
• National Center 33%
• Pairwise Comparison 33%
• Annotation Database 33%
• Protein Database 33%
• Intellectual Disability 33%
• Sequence Data 33%
• Knowledge Integration 33%
• Flexible Tool 33%
• Genomic Location 33%
• Project Data 33%
• Small Sample Size 33%
• NHLBI 33%
• Functional Regions 33%
• UCSC Genome Browser 33%
• Molecular Interactions 33%
• Low Coverage 33%
• Biological Data 33%
• DbSNP 33%
• European Ancestry 33%
• Multiple Organs 33%
• Genomic Data 33%
• Population Stratification 33%
• Causative Variant 33%
• Public Database 33%
• Comprehensive Knowledge 33%
• Congenital Disorders 33%
• Reactome 33%
• Complete Genomics 33%
• Type I Error Rate 33%
• NETPATH 33%
• DbGaP 33%
• Collapse Mechanism 33%
• Knowledge-guided 33%
• Association Testing 33%
• Entrez 33%
• Interaction Database 33%

Biochemistry, Genetics and Molecular Biology

• Bioinformatics 100%
• Rare Variant 100%
• Gene Ontology 66%
• Evolution 66%
• Signal Transduction 33%
• Protein Family 33%
• Candidate Gene 33%
• Knowledge Base 33%
• Molecular Interaction 33%
• Pharmacogenomics 33%
• Sample Size 33%
• Intellectual Disability 33%
• Exome Sequencing 33%
• Biological Database 33%