Biological Properties of Curcumin-Cellular and Molecular Mechanisms of Action

Bina Joe, M. Vijaykumar, B. R. Lokesh

Research output: Contribution to journalReview articlepeer-review

657 Scopus citations


Curcuminoids, a group of phenolic compounds isolated from the roots of Curcuma longa (Zingiberaceae), exhibit a variety of beneficial effects on health and on events that help in preventing certain diseases. A vast majority of these studies were carried out with curcumin (diferuloyl methane), which is a major curcuminoid. The most detailed studies using curcumin include anti-inflammatory, antioxidant, anticarcinogenic, antiviral, and antiinfectious activities. In addition, the wound healing and detoxifying properties of curcumin have also received considerable attention. As a result of extensive research on the therapeutic properties of curcumin, some understanding on the cellular, molecular, and biochemical mechanism of action of curcumin is emerging. These findings are summarized in this review.

Original languageEnglish (US)
Pages (from-to)97-111
Number of pages15
JournalCritical reviews in food science and nutrition
Issue number2
StatePublished - 2004

All Science Journal Classification (ASJC) codes

  • Food Science
  • Industrial and Manufacturing Engineering


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