Biomarkers for Primary Sjögren's Syndrome

Weiqian Chen; Heng Cao; Jin Lin; Nancy Olsen; Song Guo Zheng

doi:10.1016/j.gpb.2015.06.002

Biomarkers for Primary Sjögren's Syndrome

Weiqian Chen, Heng Cao, Jin Lin, Nancy Olsen, Song Guo Zheng

Research output: Contribution to journal › Review article › peer-review

45 Scopus citations

Abstract

Primary Sjögren's syndrome (pSS) is a systemic autoimmune disease with exocrine gland dysfunction and multi-organ involvement. Recent progress in understanding the pathogenesis of pSS offers an opportunity to find new biomarkers for the diagnosis and assessment of disease activity. Screening noninvasive biomarkers from the saliva and tears has significant potential. The need for specific and sensitive biomarker candidates in pSS is significant. This review aims to summarize recent advances in the identification of biomarkers of Sjögren syndrome, trying to identify reliable, sensitive, and specific biomarkers that can be used to guide treatment decisions.

Original language	English (US)
Pages (from-to)	219-223
Number of pages	5
Journal	Genomics, Proteomics and Bioinformatics
Volume	13
Issue number	4
DOIs	https://doi.org/10.1016/j.gpb.2015.06.002
State	Published - Aug 2015

All Science Journal Classification (ASJC) codes

Biochemistry
Molecular Biology
Genetics
Computational Mathematics

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10.1016/j.gpb.2015.06.002

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title = "Biomarkers for Primary Sj{\"o}gren's Syndrome",

abstract = "Primary Sj{\"o}gren's syndrome (pSS) is a systemic autoimmune disease with exocrine gland dysfunction and multi-organ involvement. Recent progress in understanding the pathogenesis of pSS offers an opportunity to find new biomarkers for the diagnosis and assessment of disease activity. Screening noninvasive biomarkers from the saliva and tears has significant potential. The need for specific and sensitive biomarker candidates in pSS is significant. This review aims to summarize recent advances in the identification of biomarkers of Sj{\"o}gren syndrome, trying to identify reliable, sensitive, and specific biomarkers that can be used to guide treatment decisions.",

author = "Weiqian Chen and Heng Cao and Jin Lin and Nancy Olsen and Zheng, {Song Guo}",

note = "Publisher Copyright: {\textcopyright} 2015 The Authors.",

year = "2015",

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doi = "10.1016/j.gpb.2015.06.002",

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AU - Chen, Weiqian

AU - Cao, Heng

AU - Lin, Jin

AU - Olsen, Nancy

AU - Zheng, Song Guo

PY - 2015/8

Y1 - 2015/8

N2 - Primary Sjögren's syndrome (pSS) is a systemic autoimmune disease with exocrine gland dysfunction and multi-organ involvement. Recent progress in understanding the pathogenesis of pSS offers an opportunity to find new biomarkers for the diagnosis and assessment of disease activity. Screening noninvasive biomarkers from the saliva and tears has significant potential. The need for specific and sensitive biomarker candidates in pSS is significant. This review aims to summarize recent advances in the identification of biomarkers of Sjögren syndrome, trying to identify reliable, sensitive, and specific biomarkers that can be used to guide treatment decisions.

AB - Primary Sjögren's syndrome (pSS) is a systemic autoimmune disease with exocrine gland dysfunction and multi-organ involvement. Recent progress in understanding the pathogenesis of pSS offers an opportunity to find new biomarkers for the diagnosis and assessment of disease activity. Screening noninvasive biomarkers from the saliva and tears has significant potential. The need for specific and sensitive biomarker candidates in pSS is significant. This review aims to summarize recent advances in the identification of biomarkers of Sjögren syndrome, trying to identify reliable, sensitive, and specific biomarkers that can be used to guide treatment decisions.

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JO - Genomics, Proteomics and Bioinformatics

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Biomarkers for Primary Sjögren's Syndrome

Abstract

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