Biomarkers for Primary Sjögren's Syndrome

Weiqian Chen, Heng Cao, Jin Lin, Nancy Olsen, Song Guo Zheng

Research output: Contribution to journalReview articlepeer-review

39 Scopus citations


Primary Sjögren's syndrome (pSS) is a systemic autoimmune disease with exocrine gland dysfunction and multi-organ involvement. Recent progress in understanding the pathogenesis of pSS offers an opportunity to find new biomarkers for the diagnosis and assessment of disease activity. Screening noninvasive biomarkers from the saliva and tears has significant potential. The need for specific and sensitive biomarker candidates in pSS is significant. This review aims to summarize recent advances in the identification of biomarkers of Sjögren syndrome, trying to identify reliable, sensitive, and specific biomarkers that can be used to guide treatment decisions.

Original languageEnglish (US)
Pages (from-to)219-223
Number of pages5
JournalGenomics, Proteomics and Bioinformatics
Issue number4
StatePublished - Aug 2015

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Molecular Biology
  • Genetics
  • Computational Mathematics


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