Bionic artificial skin with a fully implantable wireless tactile sensory system for wound healing and restoring skin tactile function

Kyowon Kang, Seongryeol Ye, Chanho Jeong, Jinmo Jeong, Yeong sinn Ye, Jin Young Jeong, Yu Jin Kim, Selin Lim, Tae Hee Kim, Kyung Yeun Kim, Jong Uk Kim, Gwan In Kim, Do Hoon Chun, Kiho Kim, Jaejin Park, Jung Hoon Hong, Byeonghak Park, Kyubeen Kim, Sujin Jung, Kyeongrim BaekDongjun Cho, Jin Yoo, Kangwon Lee, Huanyu Cheng, Byung Wook Min, Hyun Jae Kim, Hojeong Jeon, Hyunjung Yi, Tae il Kim, Ki Jun Yu, Youngmee Jung

Research output: Contribution to journalArticlepeer-review

5 Scopus citations

Abstract

Tactile function is essential for human life as it enables us to recognize texture and respond to external stimuli, including potential threats with sharp objects that may result in punctures or lacerations. Severe skin damage caused by severe burns, skin cancer, chemical accidents, and industrial accidents damage the structure of the skin tissue as well as the nerve system, resulting in permanent tactile sensory dysfunction, which significantly impacts an individual’s daily life. Here, we introduce a fully-implantable wireless powered tactile sensory system embedded artificial skin (WTSA), with stable operation, to restore permanently damaged tactile function and promote wound healing for regenerating severely damaged skin. The fabricated WTSA facilitates (i) replacement of severely damaged tactile sensory with broad biocompatibility, (ii) promoting of skin wound healing and regeneration through collagen and fibrin-based artificial skin (CFAS), and (iii) minimization of foreign body reaction via hydrogel coating on neural interface electrodes. Furthermore, the WTSA shows a stable operation as a sensory system as evidenced by the quantitative analysis of leg movement angle and electromyogram (EMG) signals in response to varying intensities of applied pressures.

Original languageEnglish (US)
Article number10
JournalNature communications
Volume15
Issue number1
DOIs
StatePublished - Dec 2024

All Science Journal Classification (ASJC) codes

  • General Chemistry
  • General Biochemistry, Genetics and Molecular Biology
  • General Physics and Astronomy

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