Blood Flow measurements using self-mixing laser diode: Effect of hematocrit level and background reflectance on measuerements

Sahin Kaya Ozdemir; Sotetsu Takamiya; Satoshi Ito; Shigenobu Shinohara; Hirofumi Yoshida

doi:10.1109/CLEOPR.1999.817945

Blood Flow measurements using self-mixing laser diode: Effect of hematocrit level and background reflectance on measuerements

Sahin Kaya Ozdemir
, Sotetsu Takamiya
, Satoshi Ito
, Shigenobu Shinohara
, Hirofumi Yoshida

Engineering Science and Mechanics

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Abstract

Recently, we demonstrated that the speckle signal from a self-mixing laser diode (SM-LD) can be used for non-invasive measurements of relative blood flow in the human body. The measurement of blood flow is based on counting the number of the intensity changes in the speckle signal of an SM-LD in a predetermined time interval and calculating the mean speckle frequency. It was shown by performing measurements on healthy human volunteers that the mean speckle frequency is higher in the areas where blood flow is active (e.g. enhanced flow, along observable vessels, healthy scabs) but has smaller values on the areas where blood flow is not active or restricted (e.g. areas with non-observable vessels). The blood flow velocity obtained on those measurements is a relative value but it has consistent linear relation characteristics with the mean flow velocity. In this paper, we study the effect of background reflectance and hematocrit level of the blood on the mean speckle frequency by a simple model. On the basis of the results, we discuss the possibility of calibrating the measurements to get an idea on the absolute velocity measurements.

Original language	English (US)
Title of host publication	CLEO/Pacific Rim 1999 - Pacific Rim Conference on Lasers and Electro-Optics
Publisher	Institute of Electrical and Electronics Engineers Inc.
Pages	1008-1009
Number of pages	2
ISBN (Electronic)	0780356616, 9780780356610
DOIs	https://doi.org/10.1109/CLEOPR.1999.817945
State	Published - 1999
Event	1999 Pacific Rim Conference on Lasers and Electro-Optics, CLEO/Pacific Rim 1999 - Seoul, Korea, Republic of Duration: Aug 30 1999 → Sep 3 1999

Publication series

Name	CLEO/Pacific Rim 1999 - Pacific Rim Conference on Lasers and Electro-Optics
Volume	3

Other

Other	1999 Pacific Rim Conference on Lasers and Electro-Optics, CLEO/Pacific Rim 1999
Country/Territory	Korea, Republic of
City	Seoul
Period	8/30/99 → 9/3/99

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

All Science Journal Classification (ASJC) codes

Electronic, Optical and Magnetic Materials
Atomic and Molecular Physics, and Optics
Computer Networks and Communications
General Physics and Astronomy

Access to Document

10.1109/CLEOPR.1999.817945

Cite this

Ozdemir, S. K., Takamiya, S., Ito, S., Shinohara, S., & Yoshida, H. (1999). Blood Flow measurements using self-mixing laser diode: Effect of hematocrit level and background reflectance on measuerements. In CLEO/Pacific Rim 1999 - Pacific Rim Conference on Lasers and Electro-Optics (pp. 1008-1009). Article 817945 (CLEO/Pacific Rim 1999 - Pacific Rim Conference on Lasers and Electro-Optics; Vol. 3). Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/CLEOPR.1999.817945

Ozdemir, Sahin Kaya ; Takamiya, Sotetsu ; Ito, Satoshi et al. / Blood Flow measurements using self-mixing laser diode : Effect of hematocrit level and background reflectance on measuerements. CLEO/Pacific Rim 1999 - Pacific Rim Conference on Lasers and Electro-Optics. Institute of Electrical and Electronics Engineers Inc., 1999. pp. 1008-1009 (CLEO/Pacific Rim 1999 - Pacific Rim Conference on Lasers and Electro-Optics).

@inproceedings{4e7e205d42fc4f26b5c7d7eef3ef7335,

title = "Blood Flow measurements using self-mixing laser diode: Effect of hematocrit level and background reflectance on measuerements",

abstract = "Recently, we demonstrated that the speckle signal from a self-mixing laser diode (SM-LD) can be used for non-invasive measurements of relative blood flow in the human body. The measurement of blood flow is based on counting the number of the intensity changes in the speckle signal of an SM-LD in a predetermined time interval and calculating the mean speckle frequency. It was shown by performing measurements on healthy human volunteers that the mean speckle frequency is higher in the areas where blood flow is active (e.g. enhanced flow, along observable vessels, healthy scabs) but has smaller values on the areas where blood flow is not active or restricted (e.g. areas with non-observable vessels). The blood flow velocity obtained on those measurements is a relative value but it has consistent linear relation characteristics with the mean flow velocity. In this paper, we study the effect of background reflectance and hematocrit level of the blood on the mean speckle frequency by a simple model. On the basis of the results, we discuss the possibility of calibrating the measurements to get an idea on the absolute velocity measurements.",

author = "Ozdemir, \{Sahin Kaya\} and Sotetsu Takamiya and Satoshi Ito and Shigenobu Shinohara and Hirofumi Yoshida",

note = "Publisher Copyright: {\textcopyright} 1999 IEEE.; 1999 Pacific Rim Conference on Lasers and Electro-Optics, CLEO/Pacific Rim 1999 ; Conference date: 30-08-1999 Through 03-09-1999",

year = "1999",

doi = "10.1109/CLEOPR.1999.817945",

language = "English (US)",

series = "CLEO/Pacific Rim 1999 - Pacific Rim Conference on Lasers and Electro-Optics",

publisher = "Institute of Electrical and Electronics Engineers Inc.",

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Ozdemir, SK, Takamiya, S, Ito, S, Shinohara, S & Yoshida, H 1999, Blood Flow measurements using self-mixing laser diode: Effect of hematocrit level and background reflectance on measuerements. in CLEO/Pacific Rim 1999 - Pacific Rim Conference on Lasers and Electro-Optics., 817945, CLEO/Pacific Rim 1999 - Pacific Rim Conference on Lasers and Electro-Optics, vol. 3, Institute of Electrical and Electronics Engineers Inc., pp. 1008-1009, 1999 Pacific Rim Conference on Lasers and Electro-Optics, CLEO/Pacific Rim 1999, Seoul, Korea, Republic of, 8/30/99. https://doi.org/10.1109/CLEOPR.1999.817945

Blood Flow measurements using self-mixing laser diode: Effect of hematocrit level and background reflectance on measuerements. / Ozdemir, Sahin Kaya; Takamiya, Sotetsu; Ito, Satoshi et al.
CLEO/Pacific Rim 1999 - Pacific Rim Conference on Lasers and Electro-Optics. Institute of Electrical and Electronics Engineers Inc., 1999. p. 1008-1009 817945 (CLEO/Pacific Rim 1999 - Pacific Rim Conference on Lasers and Electro-Optics; Vol. 3).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

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T1 - Blood Flow measurements using self-mixing laser diode

T2 - 1999 Pacific Rim Conference on Lasers and Electro-Optics, CLEO/Pacific Rim 1999

AU - Ozdemir, Sahin Kaya

AU - Takamiya, Sotetsu

AU - Ito, Satoshi

AU - Shinohara, Shigenobu

AU - Yoshida, Hirofumi

PY - 1999

Y1 - 1999

N2 - Recently, we demonstrated that the speckle signal from a self-mixing laser diode (SM-LD) can be used for non-invasive measurements of relative blood flow in the human body. The measurement of blood flow is based on counting the number of the intensity changes in the speckle signal of an SM-LD in a predetermined time interval and calculating the mean speckle frequency. It was shown by performing measurements on healthy human volunteers that the mean speckle frequency is higher in the areas where blood flow is active (e.g. enhanced flow, along observable vessels, healthy scabs) but has smaller values on the areas where blood flow is not active or restricted (e.g. areas with non-observable vessels). The blood flow velocity obtained on those measurements is a relative value but it has consistent linear relation characteristics with the mean flow velocity. In this paper, we study the effect of background reflectance and hematocrit level of the blood on the mean speckle frequency by a simple model. On the basis of the results, we discuss the possibility of calibrating the measurements to get an idea on the absolute velocity measurements.

AB - Recently, we demonstrated that the speckle signal from a self-mixing laser diode (SM-LD) can be used for non-invasive measurements of relative blood flow in the human body. The measurement of blood flow is based on counting the number of the intensity changes in the speckle signal of an SM-LD in a predetermined time interval and calculating the mean speckle frequency. It was shown by performing measurements on healthy human volunteers that the mean speckle frequency is higher in the areas where blood flow is active (e.g. enhanced flow, along observable vessels, healthy scabs) but has smaller values on the areas where blood flow is not active or restricted (e.g. areas with non-observable vessels). The blood flow velocity obtained on those measurements is a relative value but it has consistent linear relation characteristics with the mean flow velocity. In this paper, we study the effect of background reflectance and hematocrit level of the blood on the mean speckle frequency by a simple model. On the basis of the results, we discuss the possibility of calibrating the measurements to get an idea on the absolute velocity measurements.

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DO - 10.1109/CLEOPR.1999.817945

M3 - Conference contribution

AN - SCOPUS:0033325826

T3 - CLEO/Pacific Rim 1999 - Pacific Rim Conference on Lasers and Electro-Optics

SP - 1008

EP - 1009

BT - CLEO/Pacific Rim 1999 - Pacific Rim Conference on Lasers and Electro-Optics

PB - Institute of Electrical and Electronics Engineers Inc.

Y2 - 30 August 1999 through 3 September 1999

ER -

Ozdemir SK, Takamiya S, Ito S, Shinohara S, Yoshida H. Blood Flow measurements using self-mixing laser diode: Effect of hematocrit level and background reflectance on measuerements. In CLEO/Pacific Rim 1999 - Pacific Rim Conference on Lasers and Electro-Optics. Institute of Electrical and Electronics Engineers Inc. 1999. p. 1008-1009. 817945. (CLEO/Pacific Rim 1999 - Pacific Rim Conference on Lasers and Electro-Optics). doi: 10.1109/CLEOPR.1999.817945

Blood Flow measurements using self-mixing laser diode: Effect of hematocrit level and background reflectance on measuerements

Abstract

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