TY - JOUR
T1 - Bone Status among Postmenopausal Women with Different Habitual Caffeine Intakes
T2 - A Longitudinal Investigation
AU - Lloyd, Tom
AU - Johnson-Rollings, Nan
AU - Mauger, Elizabeth A.
AU - Cusatis, Deborah Cardamone
AU - Eggli, Douglas F.
AU - Kieselhorst, Kessey
PY - 2000/4/1
Y1 - 2000/4/1
N2 - Objective: Caffeine consumption has been proposed as a risk factor for bone loss in postmenopausal women. Past epidemiologic studies on caffeine and bone have been confounded by covariates including cigarette and alcohol use, differing levels of physical activity and hormone replacement therapy. The purpose of the study was to use a longitudinal design to determine the relationship between habitual dietary caffeine intake and postmenopausal bone status. Methods: Data were collected at two time points separated by two years; 138 women with little or no exposure to tobacco or to drugs known to affect bone status were seen at Visit 1, and 112 returned for Visit 2. Ninety-two of these subjects had received no drugs known to affect bone status over the two-year interval and were kept in the sample. Nutrient and caffeine intake were assessed from three-day diet records. Bone measurements were made by dual energy x-ray absorptiometry (DXA). Results: Correlation analyses indicated no association between dietary caffeine intake and total body or femoral neck bone density or bone mass. Similarly, no associations were found between caffeine consumption and longitudinal changes in total body or femoral neck bone measurements. These results held true both with and without statistical adjustment for calcium intake. Conclusions: This study does not support the idea that caffeine is a risk factor for bone loss in healthy postmenopausal women.
AB - Objective: Caffeine consumption has been proposed as a risk factor for bone loss in postmenopausal women. Past epidemiologic studies on caffeine and bone have been confounded by covariates including cigarette and alcohol use, differing levels of physical activity and hormone replacement therapy. The purpose of the study was to use a longitudinal design to determine the relationship between habitual dietary caffeine intake and postmenopausal bone status. Methods: Data were collected at two time points separated by two years; 138 women with little or no exposure to tobacco or to drugs known to affect bone status were seen at Visit 1, and 112 returned for Visit 2. Ninety-two of these subjects had received no drugs known to affect bone status over the two-year interval and were kept in the sample. Nutrient and caffeine intake were assessed from three-day diet records. Bone measurements were made by dual energy x-ray absorptiometry (DXA). Results: Correlation analyses indicated no association between dietary caffeine intake and total body or femoral neck bone density or bone mass. Similarly, no associations were found between caffeine consumption and longitudinal changes in total body or femoral neck bone measurements. These results held true both with and without statistical adjustment for calcium intake. Conclusions: This study does not support the idea that caffeine is a risk factor for bone loss in healthy postmenopausal women.
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U2 - 10.1080/07315724.2000.10718924
DO - 10.1080/07315724.2000.10718924
M3 - Article
C2 - 10763907
AN - SCOPUS:0034069604
SN - 0731-5724
VL - 19
SP - 256
EP - 261
JO - Journal of the American College of Nutrition
JF - Journal of the American College of Nutrition
IS - 2
ER -
