TY - JOUR
T1 - Bottom-up assembly of large-area nanowire resonator arrays
AU - Li, Mingwei
AU - Bhiladvala, Rustom B.
AU - Morrow, Thomas J.
AU - Sioss, James A.
AU - Lew, Kok Keong
AU - Redwing, Joan M.
AU - Keating, Christine D.
AU - Mayer, Theresa S.
N1 - Funding Information:
We acknowledge primary support from the National Institutes of Health (CA118591). Additional support was provided by the National Science Foundation (DMR-0213623, CHE-0304575, CCR-0303976), and Tobacco Settlement funds from the Pennsylvania Department of Health, which specifically disclaims responsibility for any analyses, interpretations, or conclusions. C.D.K. received partial support from the National Institutes of Health (R01 EB00268). The authors also acknowledge use of facilities at the Penn State University site of the National Science Foundation National Nanotechnology Infrastructure Network. Correspondence and requests for materials should be addressed to R.B.B. and T.S.M. Supplementary information accompanies this paper on www.nature.com/naturenanotechnology.
PY - 2008/2
Y1 - 2008/2
N2 - Directed-assembly of nanowire-based devices will enable the development of integrated circuits with new functions that extend well beyond mainstream digital logic. For example, nanoelectromechanical resonators are very attractive for chip-based sensor arrays because of their potential for ultrasensitive mass detection. In this letter, we introduce a new bottom-up assembly method to fabricate large-area nanoelectromechanical arrays each having over 2,000 single-nanowire resonators. The nanowires are synthesized and chemically functionalized before they are integrated onto a silicon chip at predetermined locations. Peptide nucleic acid probe molecules attached to the nanowires before assembly maintain their binding selectivity and recognize complementary oligonucleotide targets once the resonator array is assembled. The two types of cantilevered resonators we integrated here using silicon and rhodium nanowires had Q-factors of ∼4,500 and ∼1,150, respectively, in vacuum. Taken together, these results show that bottom-up nanowire assembly can offer a practical alternative to top-down fabrication for sensitive chip-based detection.
AB - Directed-assembly of nanowire-based devices will enable the development of integrated circuits with new functions that extend well beyond mainstream digital logic. For example, nanoelectromechanical resonators are very attractive for chip-based sensor arrays because of their potential for ultrasensitive mass detection. In this letter, we introduce a new bottom-up assembly method to fabricate large-area nanoelectromechanical arrays each having over 2,000 single-nanowire resonators. The nanowires are synthesized and chemically functionalized before they are integrated onto a silicon chip at predetermined locations. Peptide nucleic acid probe molecules attached to the nanowires before assembly maintain their binding selectivity and recognize complementary oligonucleotide targets once the resonator array is assembled. The two types of cantilevered resonators we integrated here using silicon and rhodium nanowires had Q-factors of ∼4,500 and ∼1,150, respectively, in vacuum. Taken together, these results show that bottom-up nanowire assembly can offer a practical alternative to top-down fabrication for sensitive chip-based detection.
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U2 - 10.1038/nnano.2008.26
DO - 10.1038/nnano.2008.26
M3 - Article
C2 - 18654467
AN - SCOPUS:38949169541
SN - 1748-3387
VL - 3
SP - 88
EP - 92
JO - Nature nanotechnology
JF - Nature nanotechnology
IS - 2
ER -