TY - JOUR
T1 - Brain hemispheric involvement in visuospatial and verbal divergent thinking
AU - Chen, Qunlin
AU - Beaty, Roger E.
AU - Cui, Z.
AU - Sun, Jiangzhou
AU - He, Hong
AU - Zhuang, Kaixiang
AU - Ren, Zhiting
AU - Liu, Guangyuan
AU - Qiu, J.
N1 - Funding Information:
This research was supported by the National Natural Science Foundation of China ( NSFC 31571137 ; NSFC 31500885 ; NSFC 31600878 ; NSFC 31771231 ), Chang Jiang Scholars Program , National Outstanding Young People Plan , the Program for the Top Young Talents by Chongqing , the Fundamental Research Funds for the Central Universities ( SWU1609177 ), Natural Science Foundation of Chongqing ( cstc2015jcyjA10106 ), Fok Ying Tung Education Foundation (No. 151023 ), the Research Program Funds of the Collaborative Innovation Center of Assessment toward Basic Education Quality at Beijing Normal University . Q. Chen was supported by National Science Foundation of China ( NSFC 31800919 ), China Postdoctoral Science Foundation ( 2017M622935 ) and the Fundamental Research Funds for the Central Universities ( SWU1809211 ). G. Liu was supported by National Science Foundation of China ( NSFC 61472330 and 61872301 ).
Publisher Copyright:
© 2019 Elsevier Inc.
PY - 2019/11/15
Y1 - 2019/11/15
N2 - Hemispheric lateralization for creative thinking remains a controversial topic. Early behavioral and neuroimaging research supported right hemisphere dominance in creative thinking, but more recent evidence suggests the left hemisphere plays an equally important role. In addition, the extent to which hemispheric lateralization in specific brain regions relates to individual creative ability, and whether hemispheric dominance relates to distinct task performance, remain poorly understood. Here, using multivariate predictive modeling of resting-state functional MRI data in a large sample of adults (N = 502), we estimated hemispheric segregation and integration for each brain region and investigated these lateralization indices with respect to individual differences in visuospatial and verbal divergent thinking. Our analyses revealed that individual visuospatial divergent thinking performance could be predicted by right-hemispheric segregation within the visual network, sensorimotor network, and some regions within the default mode network. High visuospatial divergent thinking was related to stronger functional connectivity between the visual network, fronto-parietal network, and default mode network within the right hemisphere. In contrast, high verbal divergent thinking performance could be predicted by inter-hemispheric balance within regions mainly involved in complex semantic processing (e.g., lateral temporal cortex and inferior frontal gyrus) and cognitive control processing (e.g., inferior frontal gyrus, middle frontal cortex, and superior parietal lobule). The current study suggests that two distinct forms of functional lateralization support individual differences in visuospatial and verbal divergent thinking. These findings have important implications for our understanding of hemispheric interaction mechanisms of creative thinking.
AB - Hemispheric lateralization for creative thinking remains a controversial topic. Early behavioral and neuroimaging research supported right hemisphere dominance in creative thinking, but more recent evidence suggests the left hemisphere plays an equally important role. In addition, the extent to which hemispheric lateralization in specific brain regions relates to individual creative ability, and whether hemispheric dominance relates to distinct task performance, remain poorly understood. Here, using multivariate predictive modeling of resting-state functional MRI data in a large sample of adults (N = 502), we estimated hemispheric segregation and integration for each brain region and investigated these lateralization indices with respect to individual differences in visuospatial and verbal divergent thinking. Our analyses revealed that individual visuospatial divergent thinking performance could be predicted by right-hemispheric segregation within the visual network, sensorimotor network, and some regions within the default mode network. High visuospatial divergent thinking was related to stronger functional connectivity between the visual network, fronto-parietal network, and default mode network within the right hemisphere. In contrast, high verbal divergent thinking performance could be predicted by inter-hemispheric balance within regions mainly involved in complex semantic processing (e.g., lateral temporal cortex and inferior frontal gyrus) and cognitive control processing (e.g., inferior frontal gyrus, middle frontal cortex, and superior parietal lobule). The current study suggests that two distinct forms of functional lateralization support individual differences in visuospatial and verbal divergent thinking. These findings have important implications for our understanding of hemispheric interaction mechanisms of creative thinking.
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U2 - 10.1016/j.neuroimage.2019.116065
DO - 10.1016/j.neuroimage.2019.116065
M3 - Article
C2 - 31398434
AN - SCOPUS:85070639462
SN - 1053-8119
VL - 202
JO - NeuroImage
JF - NeuroImage
M1 - 116065
ER -