TY - JOUR
T1 - Building complex glycopeptides
T2 - Development of a cysteine-free native chemical ligation protocol
AU - Wu, Bin
AU - Chen, Jiehao
AU - Warren, J. David
AU - Chen, Gong
AU - Hua, Zihao
AU - Danishefsky, Samuel J.
PY - 2006/6/19
Y1 - 2006/6/19
N2 - (Figure Presented) The missing link: Reiterative ligations based on non-cysteine and cysteine-based acyl acceptors have been used to prepare synthetic polypeptides and proteins with multiple sites of glycosylation. Highly complex positionally defined glycopolypeptides corresponding to single glycoforms can be formed from simple components.
AB - (Figure Presented) The missing link: Reiterative ligations based on non-cysteine and cysteine-based acyl acceptors have been used to prepare synthetic polypeptides and proteins with multiple sites of glycosylation. Highly complex positionally defined glycopolypeptides corresponding to single glycoforms can be formed from simple components.
UR - http://www.scopus.com/inward/record.url?scp=33745263964&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=33745263964&partnerID=8YFLogxK
U2 - 10.1002/anie.200600538
DO - 10.1002/anie.200600538
M3 - Article
C2 - 16710874
AN - SCOPUS:33745263964
SN - 1433-7851
VL - 45
SP - 4116
EP - 4125
JO - Angewandte Chemie - International Edition
JF - Angewandte Chemie - International Edition
IS - 25
ER -