TY - JOUR
T1 - Capillary Electrophoresis with indirect amperometric detection
AU - Olefirowicz, Teresa M.
AU - Ewing, Andrew G.
N1 - Funding Information:
This material is based on work supported by the National Institutes of Health under Grant No. GM37621-03 and by Shell Development, Beckman Instruments, Sterling Research Group, Monsanto Company and Lilly Research. Andrew G. Ewing is the recipient of a Presidential Young Investigator Award (CHE-8657193) and is an Alfred P. Sloan Research Fellow.
PY - 1990/1/19
Y1 - 1990/1/19
N2 - The use of indirect amperometric detection with capillary electrophoresis is demonstrated. The system consists of a porous glass coupler which allows amperometric detection at a carbon fiber electrode placed in the end of the capillary. 3,4-Dihydroxybenzylamine is added to the buffer system as a continuously eluting electrophore. Indirect amperometric detection in 9-μm I.D. capillaries provides detection limits as low as 380 attomole for the amino acid arginine. Finally, both direct and indirect amperometric detection can be accomplished simultaneously.
AB - The use of indirect amperometric detection with capillary electrophoresis is demonstrated. The system consists of a porous glass coupler which allows amperometric detection at a carbon fiber electrode placed in the end of the capillary. 3,4-Dihydroxybenzylamine is added to the buffer system as a continuously eluting electrophore. Indirect amperometric detection in 9-μm I.D. capillaries provides detection limits as low as 380 attomole for the amino acid arginine. Finally, both direct and indirect amperometric detection can be accomplished simultaneously.
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U2 - 10.1016/S0021-9673(00)97015-8
DO - 10.1016/S0021-9673(00)97015-8
M3 - Article
C2 - 2324222
AN - SCOPUS:0025137908
SN - 0021-9673
VL - 499
SP - 713
EP - 719
JO - Journal of Chromatography A
JF - Journal of Chromatography A
IS - C
ER -