Capturing Renal Cell Carcinoma Recurrences When Asymptomatic Improves Patient Survival

Suzanne B. Merrill; Brian S. Sohl; Ashiya Hamirani; Erik B. Lehman; Kathleen K. Lehman; Matthew G. Kaag; Jay D. Raman

doi:10.1016/j.clgc.2018.11.009

Capturing Renal Cell Carcinoma Recurrences When Asymptomatic Improves Patient Survival

Suzanne B. Merrill, Brian S. Sohl, Ashiya Hamirani, Erik B. Lehman, Kathleen K. Lehman, Matthew G. Kaag, Jay D. Raman

Research output: Contribution to journal › Article › peer-review

8 Scopus citations

Abstract

It remains unclear if surveillance of renal cell carcinoma (RCC) affords a survival benefit. Using 737 post-nephrectomy patients with M0 RCC, we examined whether detecting asymptomatic versus symptomatic recurrences influences mortality. Multivariable analysis showed that symptomatic recurrences were associated with a 3-fold increased risk of both overall and disease-specific mortality. These findings support that RCC surveillance provides beneficial patient outcomes.

Original language	English (US)
Pages (from-to)	132-138
Number of pages	7
Journal	Clinical Genitourinary Cancer
Volume	17
Issue number	2
DOIs	https://doi.org/10.1016/j.clgc.2018.11.009
State	Published - Apr 2019

All Science Journal Classification (ASJC) codes

Oncology
Urology

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10.1016/j.clgc.2018.11.009

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title = "Capturing Renal Cell Carcinoma Recurrences When Asymptomatic Improves Patient Survival",

abstract = "It remains unclear if surveillance of renal cell carcinoma (RCC) affords a survival benefit. Using 737 post-nephrectomy patients with M0 RCC, we examined whether detecting asymptomatic versus symptomatic recurrences influences mortality. Multivariable analysis showed that symptomatic recurrences were associated with a 3-fold increased risk of both overall and disease-specific mortality. These findings support that RCC surveillance provides beneficial patient outcomes.",

author = "Merrill, {Suzanne B.} and Sohl, {Brian S.} and Ashiya Hamirani and Lehman, {Erik B.} and Lehman, {Kathleen K.} and Kaag, {Matthew G.} and Raman, {Jay D.}",

note = "Publisher Copyright: {\textcopyright} 2018 Elsevier Inc.",

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AU - Merrill, Suzanne B.

AU - Sohl, Brian S.

AU - Hamirani, Ashiya

AU - Lehman, Erik B.

AU - Lehman, Kathleen K.

AU - Kaag, Matthew G.

AU - Raman, Jay D.

PY - 2019/4

Y1 - 2019/4

N2 - It remains unclear if surveillance of renal cell carcinoma (RCC) affords a survival benefit. Using 737 post-nephrectomy patients with M0 RCC, we examined whether detecting asymptomatic versus symptomatic recurrences influences mortality. Multivariable analysis showed that symptomatic recurrences were associated with a 3-fold increased risk of both overall and disease-specific mortality. These findings support that RCC surveillance provides beneficial patient outcomes.

AB - It remains unclear if surveillance of renal cell carcinoma (RCC) affords a survival benefit. Using 737 post-nephrectomy patients with M0 RCC, we examined whether detecting asymptomatic versus symptomatic recurrences influences mortality. Multivariable analysis showed that symptomatic recurrences were associated with a 3-fold increased risk of both overall and disease-specific mortality. These findings support that RCC surveillance provides beneficial patient outcomes.

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IS - 2

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Capturing Renal Cell Carcinoma Recurrences When Asymptomatic Improves Patient Survival

Abstract

All Science Journal Classification (ASJC) codes

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