Capturing Renal Cell Carcinoma Recurrences When Asymptomatic Improves Patient Survival

Suzanne B. Merrill; Brian S. Sohl; Ashiya Hamirani; Erik B. Lehman; Kathleen K. Lehman; Matthew G. Kaag; Jay D. Raman

doi:10.1016/j.clgc.2018.11.009

Capturing Renal Cell Carcinoma Recurrences When Asymptomatic Improves Patient Survival

Suzanne B. Merrill
, Brian S. Sohl
, Ashiya Hamirani
, Erik B. Lehman
, Kathleen K. Lehman
, Matthew G. Kaag
, Jay D. Raman

Research output: Contribution to journal › Article › peer-review

10 Scopus citations

Abstract

It remains unclear if surveillance of renal cell carcinoma (RCC) affords a survival benefit. Using 737 post-nephrectomy patients with M0 RCC, we examined whether detecting asymptomatic versus symptomatic recurrences influences mortality. Multivariable analysis showed that symptomatic recurrences were associated with a 3-fold increased risk of both overall and disease-specific mortality. These findings support that RCC surveillance provides beneficial patient outcomes.

Original language	English (US)
Pages (from-to)	132-138
Number of pages	7
Journal	Clinical Genitourinary Cancer
Volume	17
Issue number	2
DOIs	https://doi.org/10.1016/j.clgc.2018.11.009
State	Published - Apr 2019

All Science Journal Classification (ASJC) codes

Oncology
Urology

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10.1016/j.clgc.2018.11.009

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title = "Capturing Renal Cell Carcinoma Recurrences When Asymptomatic Improves Patient Survival",

abstract = "It remains unclear if surveillance of renal cell carcinoma (RCC) affords a survival benefit. Using 737 post-nephrectomy patients with M0 RCC, we examined whether detecting asymptomatic versus symptomatic recurrences influences mortality. Multivariable analysis showed that symptomatic recurrences were associated with a 3-fold increased risk of both overall and disease-specific mortality. These findings support that RCC surveillance provides beneficial patient outcomes.",

author = "Merrill, \{Suzanne B.\} and Sohl, \{Brian S.\} and Ashiya Hamirani and Lehman, \{Erik B.\} and Lehman, \{Kathleen K.\} and Kaag, \{Matthew G.\} and Raman, \{Jay D.\}",

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AU - Merrill, Suzanne B.

AU - Sohl, Brian S.

AU - Hamirani, Ashiya

AU - Lehman, Erik B.

AU - Lehman, Kathleen K.

AU - Kaag, Matthew G.

AU - Raman, Jay D.

PY - 2019/4

Y1 - 2019/4

N2 - It remains unclear if surveillance of renal cell carcinoma (RCC) affords a survival benefit. Using 737 post-nephrectomy patients with M0 RCC, we examined whether detecting asymptomatic versus symptomatic recurrences influences mortality. Multivariable analysis showed that symptomatic recurrences were associated with a 3-fold increased risk of both overall and disease-specific mortality. These findings support that RCC surveillance provides beneficial patient outcomes.

AB - It remains unclear if surveillance of renal cell carcinoma (RCC) affords a survival benefit. Using 737 post-nephrectomy patients with M0 RCC, we examined whether detecting asymptomatic versus symptomatic recurrences influences mortality. Multivariable analysis showed that symptomatic recurrences were associated with a 3-fold increased risk of both overall and disease-specific mortality. These findings support that RCC surveillance provides beneficial patient outcomes.

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UR - https://www.scopus.com/pages/publications/85058413855#tab=citedBy

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DO - 10.1016/j.clgc.2018.11.009

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AN - SCOPUS:85058413855

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IS - 2

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Capturing Renal Cell Carcinoma Recurrences When Asymptomatic Improves Patient Survival

Abstract

All Science Journal Classification (ASJC) codes

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