Cardiorenal syndrome type 5: Clinical presentation, pathophysiology and management strategies from the eleventh consensus conference of the acute dialysis quality initiative (ADQI)

Ravindra L. Mehta; Hamid Rabb; Andrew D. Shaw; Kai Singbartl; Claudio Ronco; Peter A. McCullough; John A. Kellum

doi:10.1159/000349970

Cardiorenal syndrome type 5: Clinical presentation, pathophysiology and management strategies from the eleventh consensus conference of the acute dialysis quality initiative (ADQI)

Ravindra L. Mehta, Hamid Rabb, Andrew D. Shaw, Kai Singbartl, Claudio Ronco, Peter A. McCullough, John A. Kellum

Department of Anesthesiology and Perioperative Medicine

Research output: Chapter in Book/Report/Conference proceeding › Chapter

40 Scopus citations

Abstract

Cardiorenal syndrome type 5 (CRS-5) includes conditions where there is a simultaneous involvement of the heart and kidney from a systemic disorder. Given the wide spectrum of diseases that contribute to CRS-5, several pathophysiological mechanisms are invoked representing the response of the heart and kidney to the contributing disorder that is ongoing. The nature, duration and the underlying condition of the heart and kidney strongly influence the clinical course of CRS-5. In this paper we discuss the pathophysiology of CRS-5 in the setting of sepsis as a model system for CRS-5 providing a brief overview of strategies for monitoring and therapeutic intervention. We offer a framework for reference for considering other disorders leading to CRS-5 where the development of cardiac and renal dysfunction is more insidious.

Original language	English (US)
Title of host publication	ADQI Consensus on AKI Biomarkers and Cardiorenal Syndromes
Pages	174-194
Number of pages	21
DOIs	https://doi.org/10.1159/000349970
State	Published - 2013

Publication series

Name	Contributions to Nephrology
Volume	182
ISSN (Print)	0302-5144

All Science Journal Classification (ASJC) codes

Nephrology

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10.1159/000349970

Cite this

Mehta, R. L., Rabb, H., Shaw, A. D., Singbartl, K., Ronco, C., McCullough, P. A., & Kellum, J. A. (2013). Cardiorenal syndrome type 5: Clinical presentation, pathophysiology and management strategies from the eleventh consensus conference of the acute dialysis quality initiative (ADQI). In ADQI Consensus on AKI Biomarkers and Cardiorenal Syndromes (pp. 174-194). (Contributions to Nephrology; Vol. 182). https://doi.org/10.1159/000349970

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abstract = "Cardiorenal syndrome type 5 (CRS-5) includes conditions where there is a simultaneous involvement of the heart and kidney from a systemic disorder. Given the wide spectrum of diseases that contribute to CRS-5, several pathophysiological mechanisms are invoked representing the response of the heart and kidney to the contributing disorder that is ongoing. The nature, duration and the underlying condition of the heart and kidney strongly influence the clinical course of CRS-5. In this paper we discuss the pathophysiology of CRS-5 in the setting of sepsis as a model system for CRS-5 providing a brief overview of strategies for monitoring and therapeutic intervention. We offer a framework for reference for considering other disorders leading to CRS-5 where the development of cardiac and renal dysfunction is more insidious.",

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Mehta, RL, Rabb, H, Shaw, AD, Singbartl, K, Ronco, C, McCullough, PA & Kellum, JA 2013, Cardiorenal syndrome type 5: Clinical presentation, pathophysiology and management strategies from the eleventh consensus conference of the acute dialysis quality initiative (ADQI). in ADQI Consensus on AKI Biomarkers and Cardiorenal Syndromes. Contributions to Nephrology, vol. 182, pp. 174-194. https://doi.org/10.1159/000349970

Cardiorenal syndrome type 5: Clinical presentation, pathophysiology and management strategies from the eleventh consensus conference of the acute dialysis quality initiative (ADQI). / Mehta, Ravindra L.; Rabb, Hamid; Shaw, Andrew D. et al.
ADQI Consensus on AKI Biomarkers and Cardiorenal Syndromes. 2013. p. 174-194 (Contributions to Nephrology; Vol. 182).

Research output: Chapter in Book/Report/Conference proceeding › Chapter

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Mehta RL, Rabb H, Shaw AD, Singbartl K, Ronco C, McCullough PA et al. Cardiorenal syndrome type 5: Clinical presentation, pathophysiology and management strategies from the eleventh consensus conference of the acute dialysis quality initiative (ADQI). In ADQI Consensus on AKI Biomarkers and Cardiorenal Syndromes. 2013. p. 174-194. (Contributions to Nephrology). doi: 10.1159/000349970

Cardiorenal syndrome type 5: Clinical presentation, pathophysiology and management strategies from the eleventh consensus conference of the acute dialysis quality initiative (ADQI)

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