Abstract
The Cartwright (Yt) blood group system consists of two antigens, Yta and Ytb, that result from point mutations in the acetylcholinesterase gene on chromosome 7q. Yta is a highincidence antigen, whereas its antithetical antigen, Ytb, shows much lower incidence. Anti-Yta and anti-Ytb are relatively rare. Anti-Yta is more commonly found in individuals of Jewish descent. Cartwright antibodies are rarely clinically significant; however, cases of in vivo hemolysis have been reported, suggesting that clinical significance should be interpreted on a case-by-case basis.
Original language | English (US) |
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Pages (from-to) | 49-54 |
Number of pages | 6 |
Journal | Immunohematology |
Volume | 28 |
Issue number | 2 |
State | Published - 2012 |
All Science Journal Classification (ASJC) codes
- General Medicine