Case of the Season: Invasive Apocrine Carcinoma of the Breast

Invasive apocrine carcinoma of the breast is a rare entity with an incidence of 3 or 4 cases per million women. Although apocrine breast cancers may have an aggressive clinical presentation, the 7-year cancer survival rate is the same as non-apocrine cancers. The prognosis of IAC is currently determined by conventional factors such as grade, tumor size, and nodal status. Targeted AR therapy is increasingly adopted with some positive results in clinical trials. This research may result in the development of a tailored treatment for these unusual and rare cancers.