Case study: An infection-triggered, autoimmune subtype of anorexia nervosa

Mae S. Sokol; Nicola S. Gray

doi:10.1097/00004583-199708000-00021

Case study: An infection-triggered, autoimmune subtype of anorexia nervosa

Mae S. Sokol, Nicola S. Gray

Department of Psychiatry and Behavioral Health

Research output: Contribution to journal › Article › peer-review

35 Scopus citations

Abstract

Objective: Certain cases of anorexia nervosa (AN) may be similar to the recently described subtype of childhood-onset obsessive-compulsive disorder hypothesized to be one of the pediatric infection-triggered autoimmune neuropsychiatric disorders (PITANDs). Method: Three clinical cases are reported. The first patient is a 12-year-old boy whose AN worsened acutely after a group A β-hemolytic streptococcal (GABHS) infection. His symptoms were alleviated after antibiotic treatment. Two other patients with possible PITANDs-related AN are described. Results: An infection-triggered process may contribute to the pathogenesis of a subtype of AN. Conclusions: Future research is needed to explore the nature of PITANDs and their relationship with AN.

Original language	English (US)
Pages (from-to)	1128-1133
Number of pages	6
Journal	Journal of the American Academy of Child and Adolescent Psychiatry
Volume	36
Issue number	8
DOIs	https://doi.org/10.1097/00004583-199708000-00021
State	Published - Aug 1997

All Science Journal Classification (ASJC) codes

Developmental and Educational Psychology
Psychiatry and Mental health

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10.1097/00004583-199708000-00021

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abstract = "Objective: Certain cases of anorexia nervosa (AN) may be similar to the recently described subtype of childhood-onset obsessive-compulsive disorder hypothesized to be one of the pediatric infection-triggered autoimmune neuropsychiatric disorders (PITANDs). Method: Three clinical cases are reported. The first patient is a 12-year-old boy whose AN worsened acutely after a group A β-hemolytic streptococcal (GABHS) infection. His symptoms were alleviated after antibiotic treatment. Two other patients with possible PITANDs-related AN are described. Results: An infection-triggered process may contribute to the pathogenesis of a subtype of AN. Conclusions: Future research is needed to explore the nature of PITANDs and their relationship with AN.",

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AB - Objective: Certain cases of anorexia nervosa (AN) may be similar to the recently described subtype of childhood-onset obsessive-compulsive disorder hypothesized to be one of the pediatric infection-triggered autoimmune neuropsychiatric disorders (PITANDs). Method: Three clinical cases are reported. The first patient is a 12-year-old boy whose AN worsened acutely after a group A β-hemolytic streptococcal (GABHS) infection. His symptoms were alleviated after antibiotic treatment. Two other patients with possible PITANDs-related AN are described. Results: An infection-triggered process may contribute to the pathogenesis of a subtype of AN. Conclusions: Future research is needed to explore the nature of PITANDs and their relationship with AN.

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Case study: An infection-triggered, autoimmune subtype of anorexia nervosa

Abstract

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