@inproceedings{f6f6f9cc07224b238e27b224eb71daff,
title = "Catechol-bearing polymerie nanoparticles for antioxidant therapy",
abstract = "Polymeric nanoparticles having redox-active catechol moieties, a common structural motif found in naturally-occurring antioxidants, were developed. We synthesized an amphiphilic catechol-bearing polymer that self-assembled to form nanoparticles with a diameter of 126 nm. The nanoparticles showed enhanced ROS-scavenging activity compared to the small catecholic compound dopamine. Furthermore, the nanoparticles inhibited ROS-mediated angiogenesis as shown by the endothelial cell tube formation assay and the chicken chorioallantoic membrane (CAM) assay.",
author = "Urara Hasegawa and Masaki Moriyama and Hiroshi Uyama and {Van Der Vlies}, {Andr{\'e} J.} and St{\'e}phanie Metzger and Martin Ehrbar",
note = "Publisher Copyright: {\textcopyright} 2015 Materials Research Society.; 2015 MRS Spring Meeting ; Conference date: 06-04-2015 Through 10-04-2015",
year = "2015",
doi = "10.1557/opl.2015.506",
language = "English (US)",
series = "Materials Research Society Symposium Proceedings",
publisher = "Materials Research Society",
pages = "13--18",
editor = "C. Xu and Z. Gu and S. Mitragoti",
booktitle = "Nanomaterials in Translational Medicine",
address = "United States",
}