Abstract
A two-dimensional theoretical model was developed to examine how shear flow-induced cell deformation interacted with cell adhesion kinetics in regulating leukocyte rolling. It was found that shear flow-induced cell deformation not only affected fluid energy input to the rolling cells and the viscous cytoplasm dissipation, it also greatly influenced adhesion energy dissipation by changing cell-substrate contact area. Adhesion kinetics also influenced cell rolling velocity through the adhesion energy dissipation.
| Original language | English (US) |
|---|---|
| Title of host publication | American Society of Mechanical Engineers, Bioengineering Division (Publication) BED |
| Publisher | ASME |
| Pages | 257-258 |
| Number of pages | 2 |
| Volume | 42 |
| ISBN (Print) | 0791816117 |
| State | Published - Dec 1 1999 |
| Event | 1999 Bioengineering Conference - Big Sky, MT, USA Duration: Jun 16 1999 → Jun 20 1999 |
Other
| Other | 1999 Bioengineering Conference |
|---|---|
| City | Big Sky, MT, USA |
| Period | 6/16/99 → 6/20/99 |
All Science Journal Classification (ASJC) codes
- General Engineering