TY - JOUR
T1 - Changes in rabbit cerebellar cortical and interpositus nucleus activity during acquisition, extinction, and backward classical eyelid conditioning
AU - Gould, Thomas J.
AU - Steinmetz, Joseph E.
N1 - Funding Information:
1This research was supported by a grant from the NIMH (MH44052) awarded to J.E.S. A portion of his research was presented at the 1990 meeting of the Society for Neuroscience (Gould, Sears, & Steinmetz, 1990) and constituted a portion of a doctoral dissertation presented by T.J.G. to the faculty of the Department of Psychology and Program in Neural Science at Indiana University. Thomas Gould is now at the V.A. Medical Center, Research 151, 1055 Claremont Street, Denver, CO, 80220. Correspondance and reprint requests concerning this article should be sent to Joseph E. Steinmetz, Department of Psychology, Program in Neural Science, Indiana University, Bloomington, IN 47405.
PY - 1996/1
Y1 - 1996/1
N2 - Multiple- and single-unit neuronal activities were recorded from cerebellar cortex (Larsell's lobule HVI and adjacent ansiform cortex) and the cerebellar interpositus nucleus during forward (CS-US), backward (US-CS), and explicitly unpaired classical eyeblink conditioning in several rabbits. Whereas learning-related activity was observed in the interpositus nucleus only during forward pairing of the conditioning stimuli, a variety of patterns of learning-related neuronal firings were observed in cerebellar cortex during forward, backward, and even unpaired presentations of the conditioning stimuli. These data suggest that the cerebellar cortex and the deep cerebellar nuclei play different roles during classical eyeblink conditioning.
AB - Multiple- and single-unit neuronal activities were recorded from cerebellar cortex (Larsell's lobule HVI and adjacent ansiform cortex) and the cerebellar interpositus nucleus during forward (CS-US), backward (US-CS), and explicitly unpaired classical eyeblink conditioning in several rabbits. Whereas learning-related activity was observed in the interpositus nucleus only during forward pairing of the conditioning stimuli, a variety of patterns of learning-related neuronal firings were observed in cerebellar cortex during forward, backward, and even unpaired presentations of the conditioning stimuli. These data suggest that the cerebellar cortex and the deep cerebellar nuclei play different roles during classical eyeblink conditioning.
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U2 - 10.1006/nlme.1996.0003
DO - 10.1006/nlme.1996.0003
M3 - Article
C2 - 8673404
AN - SCOPUS:0029990431
SN - 1074-7427
VL - 65
SP - 17
EP - 34
JO - Neurobiology of Learning and Memory
JF - Neurobiology of Learning and Memory
IS - 1
ER -