Characteristics of patient navigation programs in the Cancer Moonshot ACCSIS colorectal cancer screening initiative

Gloria D. Coronado, Renée M. Ferrari, Autumn Barnes, Sheila F. Castañeda, Mark Cromo, Melinda M. Davis, Mark P. Doescher, Kevin English, Jenna Hatcher, Karen E. Kim, Sarah Kobrin, David Liebovitz, Shiraz I. Mishra, Jesse N. Nodora, Wynne E. Norton, Jill M. Oliveri, Daniel S. Reuland, Sujha Subramanian, Jamie H. Thompson, Electra D. Paskett

Research output: Contribution to journalArticlepeer-review

2 Scopus citations


BACKGROUND: Although patient navigation has shown promise for increasing participation in colorectal cancer screening and follow-up, little evidence is available to guide implementation of patient navigation in clinical practice. We characterize 8 patient navigation programs being implemented as part of multi-component interventions of the National Cancer Institute's Cancer Moonshot Accelerating Colorectal Cancer Screening and Follow-Up Through Implementation Science (ACCSIS) initiative. METHODS: We developed a data collection template organized by ACCSIS framework domains. The template was populated by a representative from each of the 8 ACCSIS research projects. We report standardized descriptions of 1) the socio-ecological context in which the navigation program was being conducted, 2) navigation program characteristics, 3) activities undertaken to facilitate program implementation (eg, training), and 4) outcomes used in program evaluation. RESULTS: ACCSIS patient navigation programs varied broadly in their socio-ecological context and settings, the populations they served, and how they were implemented in practice. Six research projects adapted and implemented evidence-based patient navigation programs; the remaining projects developed new programs. Five projects began navigation when patients were due for initial colorectal cancer screening; 3 projects began navigation later in the screening process, when patients were due for follow-up colonoscopy after an abnormal stool-test result. Seven projects relied on existing clinical staff to deliver the navigation; 1 hired a centralized research navigator. All project researchers plan to evaluate the effectiveness and implementation of their programs. CONCLUSIONS: Our detailed program descriptions may facilitate cross-project comparisons and guide future implementation and evaluation of patient navigation programs in clinical practice.

Original languageEnglish (US)
Pages (from-to)680-694
Number of pages15
JournalJournal of the National Cancer Institute
Issue number6
StatePublished - Jun 8 2023

All Science Journal Classification (ASJC) codes

  • Oncology
  • Cancer Research

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