Characteristics of poliovirus type 3 strains after passage through monkey central nervous system

Z. Jarzabek; W. Sadowski; Piotr Janicki

Characteristics of poliovirus type 3 strains after passage through monkey central nervous system

Z. Jarzabek
, W. Sadowski
, Piotr Janicki

Research output: Contribution to journal › Article › peer-review

Abstract

Cercopithecus aethiops monkeys were inoculated intracerebrally with Sabin's type 3 poliovirus strain, and with strains isolated from subjects vaccinated with Leon 12a₁b and from their contacts. Samples of brain, spinal cord, kidneys, lymph nodes, blood and spinal fluid were taken. From these materials (except the kidneys) 23 poliovirus strains of type 3 were isolated. Genetic markers rct 40.3, rct 41, d and IST were determined for these strains. The changes observed in genetic markers of strains passaged through the central nervous system (CNS) of monkeys are described.

Original language	English (US)
Pages (from-to)	57-62
Number of pages	6
Journal	Acta Virologica
Volume	21
Issue number	1
State	Published - 1977

All Science Journal Classification (ASJC) codes

Immunology
Virology

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Cite this

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AU - Jarzabek, Z.

AU - Sadowski, W.

AU - Janicki, Piotr

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AB - Cercopithecus aethiops monkeys were inoculated intracerebrally with Sabin's type 3 poliovirus strain, and with strains isolated from subjects vaccinated with Leon 12a1b and from their contacts. Samples of brain, spinal cord, kidneys, lymph nodes, blood and spinal fluid were taken. From these materials (except the kidneys) 23 poliovirus strains of type 3 were isolated. Genetic markers rct 40.3, rct 41, d and IST were determined for these strains. The changes observed in genetic markers of strains passaged through the central nervous system (CNS) of monkeys are described.

UR - https://www.scopus.com/pages/publications/0017350930

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ER -

Characteristics of poliovirus type 3 strains after passage through monkey central nervous system

Abstract

All Science Journal Classification (ASJC) codes

UN SDGs

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