Characterization of cytochrome P-450-dependent aminopyrine N-demethylase in rat brain: Comparison with hepatic aminopyrine N-demethylation

Keyphrases

• Rat Brain 100%
• Cytochrome P450 (CYP450) 100%
• N-methylation 100%
• Aminopyrine N-demethylase 100%
• Aminopyrine 100%
• Carbon Dioxide 50%
• Liver 37%
• Inhibitory Effect 25%
• Microsomes 25%
• Carbon Effect 25%
• Hexobarbital 25%
• Protein Concentration 12%
• Kinetic Data 12%
• Active Compounds 12%
• Concentration-dependent 12%
• Am(III) 12%
• Optimal Activity 12%
• Hemoprotein 12%
• Benzo(a)pyrene 12%
• Microsomal Proteins 12%
• Time of Concentration 12%
• Electron Micrograph 12%
• Biphasic Kinetics 12%
• Incubation Time 12%
• Androstenedione 12%
• Hepatic Microsomes 12%
• Dithionite 12%
• Enzyme Inactivation 12%
• Nicotinamide Adenine Dinucleotide Phosphate (NADPH) 12%
• Differences Technique 12%
• Enzymatic Activity 12%
• Microsomal Enzymes 12%
• Linear Kinetics 12%
• Aniline 12%
• Spectral Binding 12%
• Kinetic Behavior 12%
• Meperidine 12%
• Microsomal Fraction 12%
• Absorbance Peak 12%
• Liver Enzymes 12%

Pharmacology, Toxicology and Pharmaceutical Science

• Cytochrome P450 100%
• Aminophenazone 100%
• Aminopyrine N Demethylase 100%
• Carbon Monoxide 50%
• Hexobarbital 25%
• Liver Enzyme 12%
• Benzo(a)pyrene 12%
• Hemoprotein 12%
• Incubation Time 12%
• Microsome Enzyme 12%
• Androstenedione 12%
• Reduced Nicotinamide Adenine Dinucleotide Phosphate 12%
• Pethidine 12%
• Dithionite 12%

Immunology and Microbiology

• Demethylation 100%
• Cytochrome 100%
• Microsome 37%
• Incubation Time 12%
• Enzyme Activity 12%
• Enzyme Inactivation 12%