TY - JOUR
T1 - Chemical measurements in Drosophila
AU - Makos, Monique A.
AU - Kuklinski, Nicholas J.
AU - Heien, Michael L.
AU - Berglund, E. Carina
AU - Ewing, Andrew G.
N1 - Funding Information:
The authors thank the National Institutes of Health (grant 5R01GM078385-02) and the Swedish National Science Foundation (VR) for support. AGE is supported by a Marie Curie Chair from the European Union’s Sixth Framework Programme.
PY - 2009
Y1 - 2009
N2 - The fruit fly, Drosophila melanogaster, has been extensively used as a model organism in genetics research and has significantly contributed to understanding molecular, cellular and evolutionary aspects of human behavior. Recently, research has focused on developing analytical methods to obtain highly sensitive chemical quantification along with spatiotemporal information from Drosophila melanogaster. We review a number of these advances in capillary electrophoresis, high-performance liquid chromatography, mass spectrometry, and technologies involving intact organisms, including in vivo electrochemistry.
AB - The fruit fly, Drosophila melanogaster, has been extensively used as a model organism in genetics research and has significantly contributed to understanding molecular, cellular and evolutionary aspects of human behavior. Recently, research has focused on developing analytical methods to obtain highly sensitive chemical quantification along with spatiotemporal information from Drosophila melanogaster. We review a number of these advances in capillary electrophoresis, high-performance liquid chromatography, mass spectrometry, and technologies involving intact organisms, including in vivo electrochemistry.
UR - http://www.scopus.com/inward/record.url?scp=71849094133&partnerID=8YFLogxK
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U2 - 10.1016/j.trac.2009.08.005
DO - 10.1016/j.trac.2009.08.005
M3 - Review article
AN - SCOPUS:71849094133
SN - 0165-9936
VL - 28
SP - 1223
EP - 1234
JO - TrAC - Trends in Analytical Chemistry
JF - TrAC - Trends in Analytical Chemistry
IS - 11
ER -